Every INS/E-numbered additive we can decode, and its status in each country we've checked so far. "Not listed" is never the same claim as "banned" — most additives here are perfectly legal in India and simply haven't been reviewed or registered in the other country at all. Each product page checks that product's own declared ingredients against this dictionary and shows only what it actually contains.
| INS | Name | Functional class | ADI (JECFA) | European Union | United States |
|---|---|---|---|---|---|
| 100 | Curcumins | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 101 | Riboflavins | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 102 | Tartrazine Synonyms: C.I.Food Yellow 4, FD and C Yellow No. 5 | Colour | JECFA (WHO/FAO) 0–10 mg/kg bw(2016) JECFA established an ADI of 0–10 mg/kg bw, on the basis of a NOAEL of 984 mg/kg bw per day for reductions in body weight in a chronic rat study, with application of a 100-fold uncertainty factor to account for interspecies and intraspecies variability. JECFA withdrew the previous ADI of 0–7.5 mg/kg bw per day. JECFA noted that the dietary exposure estimate for children aged 1–10 years was below the upper bound of the ADI and concluded that dietary exposure to tartrazine for the general population, including children, does not present a health concern. JECFA (WHO/FAO) source ↗EFSA ADI: <= 10 mg/kg bw/day In 2016, JECFA withdrew the current ADI of 0-7.5 mg/kg bw and replaced it with an ADI of 0-10 mg/kg bw on the basis of a NOAEL of 984 mg/kg bw per day for reduction in body weight in a chronic rat study and applying an uncertainty factor (UF) of 100 (JECFA, 2016). EFSA source ↗ | Eligible, with warning must carry the label: “may have an adverse effect on activity and attention in children” (EU Regulation 1333/2008, Annex V / Article 24). | Eligible Matched “FD&C YELLOW NO. 5” with food-use authorization under 74.1705, 74.2705, 74.705, 82.705 — matched by name, not a shared regulatory number. |
| 103 | Alkanet | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 104 | Quinoline yellow Synonyms: C.I. FOOD YELLOW 13 | Colour | JECFA (WHO/FAO) 0–3 mg/kg bw(2016) The Committee concluded that it was reasonable to use toxicology data on D&C Yellow No. 10 to support the database for Quinoline Yellow. The Committee established an ADI of 0–3 mg/kg bw (rounded value) for Quinoline Yellow on the basis of a NOAEL of 250 mg/kg bw per day for effects on body weight and organ weights in two long-term studies in rats on D&C Yellow No. 10. An uncertainty factor of 100 was applied to account for interspecies and intraspecies variability. The Committee concluded that dietary exposure to Quinoline Yellow for children and all other age groups does not present a health concern. JECFA (WHO/FAO) source ↗EFSA ADI: = 0.5 mg/kg bw/day The ANS Panel derived an acceptable daily intake (ADI) of 0.5 mg/kg bw applying a safety factor of 100 to a no observed adverse effect level (NOAEL) of 50 mg/kg bw per day Quinoline Yellow for effects observed in a long-term chronic toxicity/carcinogenicity study with a reproductive toxicity phase in rats (EFSA, 2009). This replaced the ADI previously established by the SCF (EC, 1984). EFSA source ↗ | Eligible, with warning must carry the label: “may have an adverse effect on activity and attention in children” (EU Regulation 1333/2008, Annex V / Article 24). | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 105 | Carthamus yellow Synonyms: Safflower Yellow, C.I. Natural Yellow | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 107 | Yellow 2G Synonyms: C.I. Food Yellow 5, C.I. Acid Yellow 17 | Colour | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 110 | Sunset yellow FCF Synonyms: CI Food Yellow 3, Orange Yellow S, CI (1975) No. 15985 | Colour | JECFA (WHO/FAO) 0–4 mg/kg bw(2011) JECFA established an ADI of 0–4 mg/kg body weight and withdrew the previous ADI of 0–2.5 mg/kg body weight. JECFA concluded that dietary exposure to Sunset Yellow FCF does not present a health concern. JECFA (WHO/FAO) source ↗EFSA ADI: = 1 mg/kg bw/day Sunset Yellow FCF has been previously evaluated by JECFA and the SCF. Both committees established an Acceptable Daily Intake (ADI) of 0-2.5 mg/kg bw/day. The Panel also notes that the 90 day rat study used by JECFA to derive the ADI also reported effects on testes weight, occurring without accompanying histological changes, although sperm morphology and sperm mobility were not analysed. The Panel concludes that these findings do give reason for re-definition of the ADI. The Panel decided to reduce the ADI, by an extra uncertainty factor of 2.5, to 1 mg/kg bw/day and to make the ADI temporary for 2 years. Within this period, clarification of the effects of Sunset Yellow FCF on the testis, sperm morphology and sperm mobility should be provided, based on a 28-day study performed according to the recently updated OECD test guideline 407. EFSA source ↗ | Eligible, with warning must carry the label: “may have an adverse effect on activity and attention in children” (EU Regulation 1333/2008, Annex V / Article 24). | Eligible Matched “FD&C YELLOW NO. 6” with food-use authorization under 74.1706, 74.2706, 74.706, 82.706 — matched by name, not a shared regulatory number. |
| 120 | Carmines Synonyms: Carmine, Cochineal carmine, C.I. Natural Red 4 | Colour | JECFA (WHO/FAO) 0-5 mg/kg bw (1982)(2000) At the fifty-fifth meeting (2000), the 1982 ADI of 0-5 mg/kg bw for carmines, as ammonium carmine or the equivalent of calcium, potassium and sodium salts, was not reconsidered and was maintained. JECFA (WHO/FAO) source ↗EFSA ADI: = 2.5 mg/kg bw/day The Panel concluded that the present dataset does not give reason to revise the ADI of 5 mg carmine (containing approximately 50% carminic acid)/kg bw, allocated by the SCF in 1983, but considered that, this ADI should only apply to cochineal extract and to carmines. The Panel concluded that this ADI should be expressed as carminic acid content, and this would correspond to 2.5 mg carminic acid/kg bw/day. The Panel concluded that this ADI does not apply to Cochineal as such. Refined exposure estimates for the non-brand loyal scenario for infants, toddlers, children, adolescents, adults and the elderly show that exposure to E 120 is below the ADI of 2.5 mg carminic acid/kg bw/day for all population groups. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 121 | Citrus red No. 2 | Colour | JECFA (WHO/FAO) NOT TO BE USED(1969) JECFA noted that Citrus Red No. 2 has been shown to have carcinogenic activity and toxicological data available were inadequate to allow the determination of s safe limit; JECFA therefore recommends that is should be used as a food additive. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CITRUS RED NO. 2” with food-use authorization under 74.302 — matched by name, not a shared regulatory number. |
| 122 | Azorubine (Carmoisine) | Colour | — | Eligible, with warning must carry the label: “may have an adverse effect on activity and attention in children” (EU Regulation 1333/2008, Annex V / Article 24). | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 123 | Amaranth Synonyms: C.I. Food Red 9, Naphtol Rot S | Colour | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 124 | Ponceau 4R (Cochineal red A) | Colour | — | Eligible, with warning must carry the label: “may have an adverse effect on activity and attention in children” (EU Regulation 1333/2008, Annex V / Article 24). | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 125 | Ponceau SX Synonyms: C.I. Food Red 1, FD and C Red No. 4 | Colour | JECFA (WHO/FAO) NO ADI ALLOCATED(1980) A multigeneration reproduction/teratology study and studies in dogs requested by JECFA at its 21st meeting were not available. Therefore no ADO could be established. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “FD&C RED NO. 4--DELISTED” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 127 | Erythrosine Synonyms: C.I. FOOD RED 14, FD AND C RED No. 3 | Colour | JECFA (WHO/FAO) 0-0.1 mg/kg bw(2018) The Committee concluded that the new data that have become available since the previous evaluation of erythrosine do not give reason to revise the ADI and confirmed the previous ADI of 0–0.1 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI: <= 0.1 mg/kg bw/day The current ADI was adopted by the JECFA (1990) and the SCF (1989). The Panel concludes that the present database does not provide a basis to revise the ADI of 0.1 mg/kg bw/day. EFSA source ↗ | Eligible | Eligible Matched “FD&C RED NO. 3” with food-use authorization under 74.1303, 74.303, 81.10 — matched by name, not a shared regulatory number. |
| 128 | Red 2G Synonyms: Azogeranine, C.I. Food Red 10 | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 129 | Allura red AC Synonyms: C.I. Food Red 17, FD and C Red No. 40 | Colour | JECFA (WHO/FAO) 0–7 mg/kg bw(2016) JECFA concluded that the new data do not give reason to revise the ADI and confirmed the ADI of 0–7 mg/kg body weight (bw). JECFA noted that the range of estimated dietary exposures to Allura Red AC for children based on reported or industry use data were below the upper bound of the ADI and concluded that dietary exposure to Allura Red AC for children and all other age groups does not present a health concern. JECFA (WHO/FAO) source ↗EFSA ADI: = 7 mg/kg bw/day The Panel concluded that the new data by themselves were insufficient at this time to change the overall weight of evidence in its 2009 opinion on the re-evaluation of Allura Red AC (E 129) as a food additive and that there is no reason to revise the ADI at this time. EFSA source ↗ | Eligible, with warning must carry the label: “may have an adverse effect on activity and attention in children” (EU Regulation 1333/2008, Annex V / Article 24). | Eligible Matched “FD&C RED NO. 40” with food-use authorization under 74.1340, 74.2340, 74.340 — matched by name, not a shared regulatory number. |
| 130 | Manascorubin | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 131 | Patent blue V Synonyms: CI Food Blue 5, Patent Blue 5, CI (1975) No. 42051 | Colour | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 132 | Indigotine (Indigo carmine) | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 133 | Brilliant blue FCF Synonyms: C.I. FOOD BLUE 2, FD and C BLUE No. 1 | Colour | JECFA (WHO/FAO) 0–6 mg/kg bw(2017) JECFA concluded that the available data support the revision of the ADI for Brilliant Blue FCF. In a long-term toxicity study in rats, a no-observed-adverse-effect level (NOAEL) of 631 mg/kg body weight (bw) per day was identified, based on a 15% decrease in mean terminal body weight and decreased survival of females at 1318 mg/kg bw per day. JECFA established an ADI of 0–6 mg/kg bw based on this NOAEL by applying an uncertainty factor of 100 for interspecies and intraspecies differences. JECFA (WHO/FAO) source ↗EFSA ADI: = 6 mg/kg bw/day In 2010, the EFSA ANS Panel set a new ADI of 6 mg/kg bw based on the reinterpretation of the chronic toxicity study that the SCF used to derive its ADI, wherein a NOAEL of 1 % in the diet (631 mg/kg bw/day) was identified for decreases in survival and terminal body weight in female rats. EFSA source ↗ | Eligible | Eligible Matched “FD&C BLUE NO. 1” with food-use authorization under 74.101, 74.1101, 74.2101, 82.101 — matched by name, not a shared regulatory number. |
| 140 | Chlorophylls Synonyms: Magnesium chlorophyll, Magnesium phaeophytin, C.I. Natural Green 3 | Colour | Eligible | Not listed Matched “CHLOROPHYLL” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. | |
| 141 | Chlorophylls and chlorophyllins, copper complexes | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 142 | Green S Synonyms: Food Green S, C.I. Food Green 4 | Colour | EFSA ADI: = 5 mg/kg bw/day The Panel considered that the present dataset on the absorption, distribution, metabolism and excretion, subchronic, reproductive, developmental and long-term toxicity and carcinogenicity do not give reason to revise the ADI of 5 mg/kg bw/day allocated by the SCF in 1984. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 143 | Fast Green FCF Synonyms: C.I. Food Green 3, FD and C Green No. 3 | Colour | JECFA (WHO/FAO) 0–25 mg/kg bw(2017) The ADI of 0–25 mg/kg bw established previously by JECFA was based on a long-term rat dietary that identified a NOAEL of 5% Fast Green FCF (equivalent to 2500 mg/kg bw per day), the highest concentration tested. JECFA concluded that the new data that had become available since the previous evaluation gave no reason to revise the ADI and confirmed the ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “FD&C GREEN NO. 3” with food-use authorization under 74.1203, 74.203, 74.2203, 82.203 — matched by name, not a shared regulatory number. |
| 150 | Caramels | — | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 150a | Caramel I – plain caramel | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 150b | Caramel II - sulfite caramel | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 150c | Caramel III - ammonia caramel | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 150d | Caramel IV - sulfite ammonia caramel | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 151 | Brilliant black (Black PN) | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 152 | Carbon black (Hydrocarbon) | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 153 | Vegetable carbon Synonyms: Vegetable black, Carbon black (vegetable sources) | Colour | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 154 | Brown FK Synonyms: C.I. Food Brown 1 | Colour | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 155 | Brown HT Synonyms: CHOCOLATE BROWN HT, C.I. FOOD BROWN 3 | Colour | EFSA ADI: = 1.5 mg/kg bw/day In 2010, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) has reevaluated Brown HT (E 155) as a food additive (EFSA, 2010a). The ANS Panel established an ADI for Brown HT E 155) of 1.5 mg/kg body weight bw/day based on the results of a long-term carcinogenicity and toxicity study in mice. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 160b | Annatto extracts Synonyms: Rocou, Orlean, Terre Orellana, L. Orange | Colour | JECFA (WHO/FAO) BIXIN: 0-12 mg/kg bw; NORBIXIN AND ITS SODIUM AND POTASSIUM SALT: 0-0.6 mg/kg bw (group ADI, expressed as norbixin)(2006) ADI for bixin is applicable to the following annatto extracts, provided they comply with the respective specifications: - solvent-extracted bixin (= 85% bixin, = 2.5% norbixin) - aqueous processed bixin (= 25% bixin, = 7% norbixin) and does not apply to oil-processed bixin (=10 % bixin) Group ADI for norbixin and its sodium and potassium salts is applicable to the following annatto extracts, provided they comply with the respective specifications: - solvent-extracted norbixin (= 85% norbixin) - alkali-processed norbixin, acid-precipitated (= 35% norbixin) and not acid precipitated (= 15% norbixin) In re-evaluating the studies of toxicity with solvent-extracted bixin (92% bixin) and solvent-extracted norbixin (91.6% norbixin) and in light of the additional compositional data, JECFA considered that ADIs could be allocated to these pigments, on the basis of studies conducted on the extracts. As no NOEL could be identified for oil-processed bixin and no compositional data were available, JECFA decided that the above evaluation could not be applied to this extract. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 160c | Paprika oleoresin Synonyms: Paprika extract, Oleoresin of paprika | Colour | Eligible | Eligible Matched “PAPRIKA OLEORESIN (CAPSICUM ANNUUM L.)” with food-use authorization under 73.345, 182.20 — matched by name, not a shared regulatory number. | |
| 160a | Carotenes | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 160d | Lycopenes | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 160e | Carotenal, beta-apo-8’- | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 160f | Carotenoic acid, ethyl ester, beta- apo-8'- | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161g | Canthaxanthin Synonyms: C.I. Food Orange 8 | Colour | EFSA ADI: = 0.03 mg/kg bw/day An ADI of 0.025 mg kg-1 bw, rounded up to 0.03 mg kg-1 bw has been established by the Scientific Committee on Food (EC, 1997). The Scientific Committee for Animal Nutrition (SCAN) endorsed the same ADI in its recent assessment (EC, 2002), which is also taken by the FEEDAP Panel for the present assessment. EFSA source ↗ | Excluded Listed in Annex II Part B but marked “(*)” — not authorised in any food category (permitted only in medicinal products under a separate directive). | Eligible Matched “CANTHAXANTHIN” with food-use authorization under 73.1075, 73.75 — matched by name, not a shared regulatory number. |
| 161a | Flavoxanthin | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161b | Luteins | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161c | Kryptoxanthin | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161d | Rubixanthin | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161e | Violoxanthin | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161f | Rhodoxanthin | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 161h | Zeaxanthins | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 162 | Beet red Synonyms: Beetroot Red | Colour | JECFA (WHO/FAO) NOT SPECIFIED(1987) JECFA noted that because nitrate is a component of beet red, it is necessary to ensure that levels of nitrate do not exceed the specifications. Under these conditions beet red could be used according to good manufacturing practice with an ADI "not specified", keeping in mind the need to limit the nitrate content of foods produced for infants and young children. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 163 | Anthocyanins Synonyms: Anthocyans | Colour | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 164 | Gardenia yellow | Colour | JECFA (WHO/FAO) NOT ALLOCATED(2014) Given the deficiencies in the toxicological database, including missing toxicological studies (e.g. long-term toxicity, carcinogenicity, reproductive toxicity and developmental toxicity studies), the inadequate characterization of the test material and limited reporting of the available studies, the Committee was unable to evaluate gardenia yellow proposed for use as a food colour. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 165 | Gardenia blue | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 166 | Sandalwood | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 170 | Calcium carbonates | Acidity regulator, Anticaking agent, Colour, Firming agent, Flour treatment agent, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 171 | Titanium dioxide Synonyms: C.I. Pigment white 6, Titania | Colour | JECFA (WHO/FAO) NOT LIMITED (not specified)(2023) At the 97th meeting, JECFA considered additional toxicological studies relevant to the safety assessment of INS 171 that investigated the toxicokinetics, acute toxicity, short-term toxicity, longterm toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing the short-term initiation/promotion potential for colon cancer. JECFA identified a number of TiO2 test materials that were considered representative of INS 171. Further, JECFA recognized that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to INS 171. These studies on non-representative materials were evaluated by JECFA , but it was concluded that they were not relevant to the safety assessment of INS 171. INS 171 was poorly absorbed from the gastrointestinal tract of mice and rats. No adverse effects were observed in short-term studies in mice and rats receiving INS 171 in the diet, with NOAELs of 15 000 mg/kg bw per day and 5000 mg/kg bw per day in mice and rats, respectively, the highest doses tested. JECFA noted that the available data did not provide convincing evidence of genotoxicity for INS 171, but recognized the limitations in current methodologies with respect to the testing of poorly soluble particulate materials. Although there were uncertainties in the genotoxicity data, JECFA took into account the fact that INS 171 was not carcinogenic in adequately conducted 2-year studies in mice and rats at doses of up to 7500 mg/kg bw per day for mice and 2500 mg/kg bw per day for rats, the highest doses tested. There was no evidence of reproductive or developmental toxicity in studies in rats at INS 171 doses up to 1000 mg/kg bw per day, the highest doses tested. Available studies in humans and postmortem analysis of tissues suggested that the oral bioavailability of TiO2 in humans is very low. JECFA noted that t JECFA (WHO/FAO) source ↗ | Excluded Listed in Annex II Part B but marked “(**)” — not authorised in any food category (permitted only in medicinal products under a separate directive). | Eligible Matched “TITANIUM DIOXIDE” with food-use authorization under 73.1575, 73.2575, 73.3126, 73.350 — matched by name, not a shared regulatory number. |
| 172 | Iron oxides | Colour | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 173 | Aluminium powder Synonyms: C.I. Pigment metal | Colour | JECFA (WHO/FAO) NO ADI ALLOCATED(1977) JECFA noted aluminum is used as silvering decoration for certain items of confectionary. The use is very limited and was not considered to present a hazard. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 174 | Silver | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 175 | Gold, metallic | Colour | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 176 | Potassium aluminium silicate-based pearlescent pigments (PAS-BPP) | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 180 | Lithol rubine BK Synonyms: C.I. Pigment Red 57, Fd and C Red No. 7, Rubinpigment, Brilliant Carmine 6B, Carmine 6B, Litholrubintoner BKL, Permanent Rubin L6B | Colour | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 181 | Tannic acid (Tannins) | Colour, Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 182 | Orchil | Colour | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 200 | Sorbic acid | Preservative | JECFA (WHO/FAO) 0-25 mg/kg bw(1973) As sum of sorbic acid and calcium, potassium and sodium sorbates (expressed as sorbic acid) JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SORBIC ACID” with food-use authorization under 172.872, 177.2260, 181.23, 182.3089 — matched by name, not a shared regulatory number. |
| 201 | Sodium sorbate | Preservative | JECFA (WHO/FAO) 0-25 mg/kg bw(1985) Group ADI for sorbic acid and its calcium, potassium and sodium salts expressed as sorbic acid JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “SODIUM SORBATE” with food-use authorization under 182.3795, 182.90 — matched by name, not a shared regulatory number. |
| 202 | Potassium sorbate | Preservative | JECFA (WHO/FAO) 0-25 mg/kg bw(1973) Group ADI as the sum of sorbic acid and calcium, potassium and sodium sorbates (expressed as sorbic acid) JECFA (WHO/FAO) source ↗EFSA ADI: = 25 mg/kg bw/day JECFA (1974) has set a group ADI for sorbic acid and sorbates of 25 mg/kg bw (expressed as sorbic acid), based on a no observed adverse effect level of 5% in the diet (highest dose tested equivalent to 2500 mg/kg bw per day) of rats from a two-generation study. The SCF (EC, 1996) endorsed this ADI. Therefore, the FEEDAP Panel considers that the use of sorbic acid and potassium sorbate up to the maximum proposed levels is safe for consumers. EFSA source ↗ | Eligible | Eligible Matched “POTASSIUM SORBATE” with food-use authorization under 182.3640, 182.90 — matched by name, not a shared regulatory number. |
| 203 | Calcium sorbate | Preservative | JECFA (WHO/FAO) 0-25 mg/kg bw(1973) Group ADI as the sum of sorbic acid and calcium, potassium and sodium sorbates (expressed as sorbic acid) JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CALCIUM SORBATE” with food-use authorization under 182.3225 — matched by name, not a shared regulatory number. |
| 209 | Heptyl para-hydroxybenzoate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 210 | Benzoic acid Synonyms: BENZENECARBOXYLIC ACID, CARBOXYBENZENE, PHENYL FORMIC ACID, DRACYLIC ACID | Preservative | JECFA (WHO/FAO) 0–20 mg/kg bw(2021) Applying a chemical specific adjustment factor of 2 for interspecies toxicokinetics variation instead of the default factor of 4.0, the Committee established a group ADI of 0–20 mg/kg bw, which applies to benzoic acid, the benzoate salts (calcium, potassium and sodium), benzaldehyde, benzyl acetate, benzyl alcohol and benzyl benzoate, expressed as benzoic acid equivalents. The Committee withdrew the previous group ADI of 0–5 mg/kg bw. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “BENZOIC ACID” with food-use authorization under 175.300, 177.1390, 184.1021 — matched by name, not a shared regulatory number. |
| 211 | Sodium benzoate | Preservative | JECFA (WHO/FAO) 0–20 mg/kg bw(2021) Applying a chemical specific adjustment factor of 2 for interspecies toxicokinetics variation instead of the default factor of 4.0, the Committee established a group ADI of 0–20 mg/kg bw, which applies to benzoic acid, the benzoate salts (calcium, potassium and sodium), benzaldehyde, benzyl acetate, benzyl alcohol and benzyl benzoate, expressed as benzoic acid equivalents. The Committee withdrew the previous group ADI of 0–5 mg/kg bw. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM BENZOATE” with food-use authorization under 181.23, 184.1733 — matched by name, not a shared regulatory number. |
| 212 | Potassium benzoate | Preservative | JECFA (WHO/FAO) 0–20 mg/kg bw(2021) Applying a chemical specific adjustment factor of 2 for interspecies toxicokinetics variation instead of the default factor of 4.0, the Committee established a group ADI of 0–20 mg/kg bw, which applies to benzoic acid, the benzoate salts (calcium, potassium and sodium), benzaldehyde, benzyl acetate, benzyl alcohol and benzyl benzoate, expressed as benzoic acid equivalents. The Committee withdrew the previous group ADI of 0–5 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI (group): = 5 mg/kg bw/day The Panel derived a group ADI of 5 mg/kg bw per day, expressed as benzoic acid, for benzoic acid (E 210), sodium benzoate (E 211), potassium benzoate (E 212) and calcium benzoate (E 213). EFSA source ↗ | Eligible | Not listed Matched “POTASSIUM BENZOATE” in the FDA inventory, but only under drug/cosmetic/device-use citations (177.1210), not as a direct food additive — matched by name, not a shared regulatory number. |
| 213 | Calcium benzoate Synonyms: Monocalcium benzoate | Preservative | JECFA (WHO/FAO) 0-5 mg/kg bw(1996) The 1996 group ADI of 0-5 mg/kg bw for benzoic acid, the benzoate salts (calcium, potassium and sodium), benzaldehyde, benzyl acetate, benzyl alcohol and benzyl benzoate, expressed as benzoic acid equivalents, was maintained at the fifty-seventh meeting (2001). JECFA (WHO/FAO) source ↗EFSA ADI (group): = 5 mg/kg bw/day The Panel derived a group ADI of 5 mg/kg bw per day, expressed as benzoic acid, for benzoic acid (E 210), sodium benzoate (E 211), potassium benzoate (E 212) and calcium benzoate (E 213). EFSA source ↗ | Eligible | Not listed Matched “CALCIUM BENZOATE” in the FDA inventory, but only under drug/cosmetic/device-use citations (178.2010), not as a direct food additive — matched by name, not a shared regulatory number. |
| 214 | Ethyl para-hydroxybenzoate | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 215 | Sodium ethyl para-hydroxybenzoate | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 216 | Propyl para-hydroxybenzoate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 217 | Sodium propyl para-hydroxybenzoate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 218 | Methyl para-hydroxybenzoate | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 219 | Sodium methyl para-hydroxybenzoate | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 220 | Sulfur dioxide | Antioxidant, Bleaching agent, Flour treatment agent, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Eligible Matched “SULFUR DIOXIDE” with food-use authorization under 73.170, 172.892, 182.3862 — matched by name, not a shared regulatory number. |
| 221 | Sodium sulfite Synonyms: Disodium sulfite | Antioxidant, Bleaching agent, Flour treatment agent, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Eligible Matched “SODIUM SULFITE” with food-use authorization under 73.85, 173.310, 177.1200, 182.3798 — matched by name, not a shared regulatory number. |
| 222 | Sodium hydrogen sulfite | Antioxidant, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM BISULFITE” with food-use authorization under 173.310, 177.1200, 182.3739 — matched by name, not a shared regulatory number. |
| 223 | Sodium metabisulfite | Antioxidant, Bleaching agent, Flour treatment agent, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Eligible Matched “SODIUM METABISULFITE” with food-use authorization under 173.310, 182.3766 — matched by name, not a shared regulatory number. |
| 224 | Potassium metabisulfite | Antioxidant, Bleaching agent, Flour treatment agent, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Eligible Matched “POTASSIUM METABISULFITE” with food-use authorization under 182.3637 — matched by name, not a shared regulatory number. |
| 225 | Potassium sulfite | Antioxidant, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “POTASSIUM SULFITE” with food-use authorization under 73.85 — matched by name, not a shared regulatory number. |
| 226 | Calcium sulfite | Antioxidant, Preservative | EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 227 | Calcium hydrogen sulfite Synonyms: Calcium bisulfite | Antioxidant, Preservative | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 228 | Potassium bisulfite | Antioxidant, Preservative | EFSA ADI (group): = 0.7 mg/kg bw/day The Panel noted several uncertainties and limitations in the database and concluded that the current group acceptable daily intake (ADI) of 0.7 mg SO2 equivalent/kg bw per day would remain adequate but should be considered temporary while the database was improved. The Panel recommended that the database and the temporary group ADI should be re-evaluated and noted that the recommended studies could require 5 years for completion. EFSA source ↗ | Eligible | Eligible Matched “POTASSIUM BISULFITE” with food-use authorization under 182.3616 — matched by name, not a shared regulatory number. |
| 230 | Diphenyl | Preservative | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “BIPHENYL” in the FDA inventory, but only under drug/cosmetic/device-use citations (178.2010), not as a direct food additive — matched by name, not a shared regulatory number. | |
| 231 | Ortho-phenylphenol | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 232 | Sodium ortho-phenylphenol | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 233 | Thiabendazole Synonyms: THIABENDAZOLE, OMNIZOLE, THIABEN, THIBENZOLE, BOVIZOLE, EPROFIL, EQUIZOLE, MINTEZOL, MERTECT, LOMBRISTOP, MINZOLUM, NEMAPAN, POLIVAL, TBZ | Preservative | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 234 | Nisin | Preservative | JECFA (WHO/FAO) 0-2 mg/kg bw(2024) Based on the available data, JECFA concluded that there is no concern for the induction of antimicrobial resistance, and that the risk of nisin having a disrupting effect on the microbiome of the human gastrointestinal tract is low. The new toxicological information available for this evaluation did not provide any reason to revise the ADI for nisin. JECFA re-affirmed the ADI of 0– 2 mg/kg bw for nisin established by the previous JECFA meeting at the Seventy-seventh meeting, but noted that the critical toxicological studies were conducted with nisin A; JECFA therefore concluded that the ADI applies only to nisin A. JECFA (WHO/FAO) source ↗EFSA ADI: = 0.13 mg/kg bw/day The SCF allocated an ADI of 0.13 mg pure nisin/kg bw for a product with a potency of 40 000 units/mg based on a reproduction study (SCF, 1992). EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 235 | Natamycin (Pimaricin) | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 236 | Formic acid | Preservative | JECFA (WHO/FAO) 0-3 mg/kg bw (1979)(1997) No safety concern at current levels of intake when used as a flavouring agent. The group ADI of 0-3 mg/kg bw that was established for formic acid and ethyl formate at the twenty-third meeting (1979) was maintained at the forty-ninth meeting (1997). JECFA (WHO/FAO) source ↗EFSA ADI (group): = 0.3 mg/kg bw A group ADI for formic acid and ethyl formate of 0-3 mg/kg b.w. has been established, and on the basis of available evidence, the CONTAM Panel considers this appropriate. Formic acid is toxic only when it is present at sufficient concentration to change the H+ concentration. The maximum potential levels of formic acid arising in fats or oils following its transport as a previous cargo would be of no concern. The CONTAM Panel therefore concludes that formic acid meets the criteria for acceptability as a previous cargo for edible fats and oils. EFSA source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “FORMIC ACID” with food-use authorization under 172.515, 172.723, 186.1316 — matched by name, not a shared regulatory number. |
| 237 | Sodium formate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “SODIUM FORMATE” in the FDA inventory, but only under drug/cosmetic/device-use citations (175.105, 186.1756), not as a direct food additive — matched by name, not a shared regulatory number. |
| 238 | Calcium formate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 239 | Hexamethylene tetramine | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 240 | Formaldehyde | Preservative | EFSA TDI: = 150 µg/kg bw/day Tolerable Daily Intake (TDI) value was set by the World Health Organisation (WHO) for drinking water. EFSA source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “FORMALDEHYDE” with food-use authorization under 173.340, 175.105, 175.210, 175.300 — matched by name, not a shared regulatory number. |
| 241 | Gum guaicum | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 242 | Dimethyl dicarbonate Synonyms: DMDC, Dimethyl pyrocarbonate | Preservative | JECFA (WHO/FAO) NOT SPECIFIED(1990) Acceptable for use as a cold sterilization agent in beverages when used according to good manufacturing practice up to a maximum concentration of 250 mg/L. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “DIMETHYL DICARBONATE” with food-use authorization under 172.133 — matched by name, not a shared regulatory number. |
| 243 | Lauric arginate ethyl ester | Preservative, Antimicrobial preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 249 | Potassium nitrite | Colour retention agent, Preservative | JECFA (WHO/FAO) 0-0.07 mg/kg bw(2002) Evaluated as nitrite and expressed as nitrite ion, ADI applies to all sources of intake but not to infants below the age of 3 months. JECFA established an ADI of 0-0.07 mg/kg/bw, expressed as nitrite ion, on the basis of the NOEL of 6.7 mg/kg bw/day for effects on the heart and lung in a 2-year study in rats and a safety factor of 100. Nitrite causes methemoglobinemia. JECFA noted that as this might occur after a single dose, it would be appreciate to establish an acute reference dose for nitrite. The data available for review at the present JECFA meeting were however not relevant for establishing an acute reference dose. JECFA (WHO/FAO) source ↗EFSA ADI: = 0.07 mg/kg bw/day The Panel concluded that an increased methaemoglobin level, observed in human and animals, was a relevant effect for the derivation of the ADI. The Panel, using a BMD approach, derived an ADI of 0.07 mg nitrite ion/kg bw per day. The exposure to nitrite resulting from its use as food additive did not exceed this ADI for the general population, except for a slight exceedance in children at the highest percentile. EFSA source ↗ | Eligible | Not listed Matched “POTASSIUM NITRITE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 250 | Sodium nitrite | Colour retention agent, Preservative | JECFA (WHO/FAO) 0-0.07 mg/kg bw(2002) Evaluated as nitrite and expressed as nitrite ion. ADI applies to all sources of intake but not to infants below the age of 3 months. JECFA established an ADI of 0-0.07 mg/kg/bw, expressed as nitrite ion, on the basis of the NOEL of 6.7 mg/kg bw/day for effects on the heart and lung in a 2-year study in rats and a safety factor of 100. Nitrite causes methemoglobinemia. JECFA noted that as this might occur after a single dose, it would be appreciate to establish an acute reference dose for nitrite. The data available for review at the present JECFA meeting were however not relevant for establishing an acute reference dose. JECFA (WHO/FAO) source ↗EFSA ADI: = 0.1 mg/kg bw/day The Panel concluded that an increased methaemoglobin level, observed in human and animals, was a relevant effect for the derivation of the ADI. Using the lowest BMDL of 9.63 mg/kg bw per day, and applying the default UF of 100, the Panel derived an ADI of 0.1 mg sodium nitrite/kg bw per day, corresponding to 0.07 mg nitrite ion/kg bw per day. The exposure to nitrite resulting from its use as food additive did not exceed this ADI for the general population, except for a slight exceedance in children at the highest percentile. EFSA source ↗ | Eligible | Eligible Matched “SODIUM NITRITE” with food-use authorization under 172.170, 172.175, 172.177, 172.820 — matched by name, not a shared regulatory number. |
| 251 | Sodium nitrate Synonyms: Chile saltpetre, Cubic or soda nitre | Colour retention agent, Preservative | JECFA (WHO/FAO) 0-3.7 mg/kg bw(1995) Expressed as nitrate ion; ADI does not apply to infants below the age of 3 months JECFA (WHO/FAO) source ↗EFSA ADI: = 3.7 mg/kg bw/day Despite the uncertainty associated with the ADI established by the SCF, the Panel concluded that currently there was insufficient evidence to withdraw this ADI. The exposure to nitrate solely from its use as a food additive was estimated to be less than 5% of the overall exposure to nitrate in food based on a refined estimated exposure scenario. This exposure did not exceed the current ADI (SCF, 1997). However, if all sources of exposure to dietary nitrate are considered (food additive, natural presence and contamination), the ADI would be exceeded for all age groups at the mean and the highest exposure. EFSA source ↗ | Eligible | Eligible Matched “SODIUM NITRATE” with food-use authorization under 172.170, 172.175, 173.310, 175.105 — matched by name, not a shared regulatory number. |
| 252 | Potassium nitrate Synonyms: Saltpetre, Nitre | Colour retention agent, Preservative | JECFA (WHO/FAO) 0-3.7 mg/kg bw(1995) Expressed as nitrate ion; ADI does not apply to infants below the age of 3 months. JECFA (WHO/FAO) source ↗EFSA ADI: = 3.7 mg/kg bw/day Despite the uncertainty associated with the ADI established by the SCF, the Panel concluded that currently there was insufficient evidence to withdraw this ADI. The exposure to nitrate solely from its use as a food additive was estimated to be less than 5% of the overall exposure to nitrate in food based on a refined estimated exposure scenario. This exposure did not exceed the current ADI (SCF, 1997). However, if all sources of exposure to dietary nitrate are considered (food additive, natural presence and contamination), the ADI would be exceeded for all age groups at the mean and the highest exposure. EFSA source ↗ | Eligible | Eligible Matched “POTASSIUM NITRATE” with food-use authorization under 172.160, 181.33, 181.34 — matched by name, not a shared regulatory number. |
| 260 | Acetic acid, glacial | Acidity regulator, Preservative | — | Eligible | Eligible Matched “ACETIC ACID” with food-use authorization under 73.85, 172.814, 173.370, 184.1005 — matched by name, not a shared regulatory number. |
| 261 | Potassium acetates | Acidity regulator, Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 262 | Sodium acetates | Acidity regulator, Preservative, Sequestrant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 263 | Calcium acetate | Acidity regulator, Preservative, Stabilizer | Eligible | Eligible Matched “CALCIUM ACETATE” with food-use authorization under 175.300, 181.29, 182.6197, 184.1185 — matched by name, not a shared regulatory number. | |
| 264 | Ammonium acetate | Acidity regulator | JECFA (WHO/FAO) NOT SPECIFIED(1982) JECFA noted that other ammonium salts and acetates have been allocated a group ADI “not specified” and JECFA concluded to include ammonium acetate within the previously accepted groups. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “AMMONIUM ACETATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 265 | Dehydroacetic acid | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “DEHYDROACETIC ACID” with food-use authorization under 172.130, 175.105 — matched by name, not a shared regulatory number. |
| 266 | Sodium dehydroacetate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “SODIUM DEHYDROACETATE” with food-use authorization under 172.130, 175.105 — matched by name, not a shared regulatory number. |
| 270 | Lactic acid, L-, D- and DL- | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 280 | Propionic acid | Preservative | JECFA (WHO/FAO) NOT LIMITED (1973)(1997) No safety concern at current levels of intake when used as a flavouring agent. The 1973 group ADI of "not limited" for propionic acid and its calcium, potassium and sodium salts was maintained at the forty-ninth meeting (1997). JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “PROPIONIC ACID” with food-use authorization under 178.1010, 184.1081 — matched by name, not a shared regulatory number. |
| 281 | Sodium propionate Synonyms: SODIUM PROPANOATE | Preservative | JECFA (WHO/FAO) NOT LIMITED(1973) The 1973 group ADI of "not limited" for propionic acid and its calcium, potassium and sodium salts was maintained at the forty-ninth meeting (1997). JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM PROPIONATE” with food-use authorization under 179.45, 180.23, 184.1784 — matched by name, not a shared regulatory number. |
| 282 | Calcium propionate Synonyms: CALCIUM PROPANOATE | Preservative | JECFA (WHO/FAO) NOT LIMITED(1973) The 1973 group ADI of "not limited" for propionic acid and its calcium, potassium and sodium salts was maintained at the forty-ninth meeting (1997). JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CALCIUM PROPIONATE” with food-use authorization under 179.45, 181.23, 184.1221 — matched by name, not a shared regulatory number. |
| 283 | Potassium propionate | Preservative | JECFA (WHO/FAO) NOT LIMITED(1973) The 1973 group ADI of "not limited" for propionic acid and its calcium, potassium and sodium salts was maintained at the forty-ninth meeting (1997). JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 290 | Carbon dioxide | Carbonating agent, Foaming agent, Packaging gas, Preservative, Propellant | Eligible | Eligible Matched “CARBON DIOXIDE” with food-use authorization under 184.1240 — matched by name, not a shared regulatory number. | |
| 296 | Malic acid, DL- | Acidity regulator | — | Eligible | Eligible Matched “MALIC ACID” with food-use authorization under 184.1069 — matched by name, not a shared regulatory number. |
| 297 | Fumaric acid Synonyms: ALLOMALEIC ACID, BOLETIC ACID, (E)-BUTENEDIOIC ACID, (E)-1,2-ETHYLENEDICARBOXYLIC ACID | Acidity regulator | JECFA (WHO/FAO) NOT SPECIFIED (1989)(1999) No safety concern at current levels of intake when used as a flavouring agent. The 1989 group ADI of "not specified" for fumaric acid and its salts was maintained at the fifty-third meeting (1999). JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “FUMARIC ACID” with food-use authorization under 172.350, 172.808, 172.810, 172.822 — matched by name, not a shared regulatory number. |
| 300 | Ascorbic acid, L- Also known as: Vitamin C Synonyms: Vitamin C | Acidity regulator, Antioxidant, Flour treatment agent, Sequestrant | JECFA (WHO/FAO) NOT SPECIFIED(1981) Group ADI for ascorbic acid and its sodium, potassium and calcium salts JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “ASCORBIC ACID” with food-use authorization under 172.280, 182.3013, 182.8013 — matched by name, not a shared regulatory number. |
| 301 | Sodium ascorbate | Antioxidant | JECFA (WHO/FAO) NOT SPECIFIED(1981) Group ADI for ascorbic acid and its sodium, potassium, and calcium salts JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM ASCORBATE” with food-use authorization under 182.3731 — matched by name, not a shared regulatory number. |
| 302 | Calcium ascorbate | Antioxidant | JECFA (WHO/FAO) NOT SPECIFIED(1981) Group ADI for ascorbic acid and its sodium, potassium and calcium salts JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CALCIUM ASCORBATE” with food-use authorization under 182.3189 — matched by name, not a shared regulatory number. |
| 303 | Potassium ascorbate | Antioxidant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 304 | Ascorbyl palmitate Synonyms: Vitamin C palmitate | Antioxidant | JECFA (WHO/FAO) NOT SPECIFIED(2025) JECFA noted new studies that showed that ascorbyl palmitate was rapidly and extensively hydrolysed pre-systemically to ascorbic acid and palmitic acid. Hydrolysis of ascorbyl palmitate is mediated by carboxylesterases, which are also expressed in neonates and infants, albeit at lower levels than in adults. On that basis, JECFA considered that systemic exposure to ascorbyl palmitate would be low for all population subgroups. JECFA withdrew the previously established ADI of 0–1.25 mg/kg bw for ascorbyl palmitate or ascorbyl stearate, or the sum of both. JECFA noted that the previous ADI for ascorbyl palmitate or ascorbyl stearate, or the sum of both, was based on toxicological data for ascorbyl palmitate, and therefore established a group ADI “not specified”b for ascorbyl palmitate or ascorbyl stearate, or the sum of both. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “ASCORBYL PALMITATE” with food-use authorization under 182.3149 — matched by name, not a shared regulatory number. |
| 305 | Ascorbyl stearate Synonyms: VITAMIN C STEARATE | Antioxidant | JECFA (WHO/FAO) NOT SPECIFIED(2025) JECFA noted new studies that showed that ascorbyl palmitate was rapidly and extensively hydrolysed pre-systemically to ascorbic acid and palmitic acid. Hydrolysis of ascorbyl palmitate is mediated by carboxylesterases, which are also expressed in neonates and infants, albeit at lower levels than in adults. On that basis, JECFA considered that systemic exposure to ascorbyl palmitate would be low for all population subgroups. JECFA withdrew the previously established ADI of 0–1.25 mg/kg bw for ascorbyl palmitate or ascorbyl stearate, or the sum of both. JECFA noted that the previous ADI for ascorbyl palmitate or ascorbyl stearate, or the sum of both, was based on toxicological data for ascorbyl palmitate, and therefore established a group ADI “not specified”b for ascorbyl palmitate or ascorbyl stearate, or the sum of both. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “ASCORBYL STEARATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 307b | Tocopherol concentrate, mixed Synonyms: Vitamin E | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 307 | Tocopherols | — | — | Eligible | Eligible Matched “TOCOPHEROLS” with food-use authorization under 182.3890, 182.8890, 182.8892, 184.1890 — matched by name, not a shared regulatory number. |
| 307a | Tocopherol, d-alpha- | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 307c | Tocopherol, dl-alpha- | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 308 | Tocopherol, gamma-, synthetic | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 309 | Tocopherol, delta-, synthetic | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 310 | Propyl gallate | Antioxidant | JECFA (WHO/FAO) 0-1.4 mg/kg bw (1993)(1996) The 1993 ADI was maintained at the forty-sixth meeting (1996) JECFA (WHO/FAO) source ↗EFSA ADI: = 0.5 mg/kg bw/day An uncertainty factor of 300 instead of 100 should be applied for extrapolation from subchronic to chronic data and due to the limitations in the reproductive toxicity database. The Panel concluded that the use of propyl gallate as food additive at the current uses and use levels is not of safety concern. EFSA source ↗ | Eligible | Eligible Matched “PROPYL GALLATE” with food-use authorization under 172.615, 175.125, 175.300, 175.380 — matched by name, not a shared regulatory number. |
| 311 | Octyl gallate | Antioxidant | JECFA (WHO/FAO) NO ADI ALLOCATED(1996) The temporary ADI allocated at the forty-first meeting (1993) was not extended JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “OCTYL GALLATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 312 | Dodecyl gallate Synonyms: Lauryl gallate | Antioxidant | JECFA (WHO/FAO) NO ADI ALLOCATED(1996) The temporary ADI allocated at the forty-first meeting (1993) was not extended JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “DODECYL GALLATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 313 | Ethyl gallate | Antioxidant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 314 | Guaiac resin Synonyms: Guaiacum, Guaiac gum, Gum guaiac, Gum guaiacum | Antioxidant | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “GUAIAC GUM (GUAIACUM SPP.)” with food-use authorization under 172.510, 175.300, 177.1010, 181.24 — matched by name, not a shared regulatory number. | |
| 315 | Erythorbic acid (Isoascorbic acid) | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 316 | Sodium erythorbate (Sodium isoascorbate) | Antioxidant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 317 | Potassium isoascorbate | Antioxidant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 318 | Calcium isoascorbate | Antioxidant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 319 | Tertiary butylhydroquinone Also known as: TBHQ Synonyms: TBHQ | Antioxidant | Eligible | Eligible Matched “TERT-BUTYLHYDROQUINONE” with food-use authorization under 172.185, 177.2420 — matched by name, not a shared regulatory number. | |
| 320 | Butylated hydroxyanisole Synonyms: BHA | Antioxidant | EFSA ADI: = 1 mg/kg bw/day In its opinion of 21 September 2011, the ANS Panel concluded that the present database does give reason to revise the ADI and established a new ADI of 1.0 mg/kg bw/day. EFSA source ↗ | Eligible | Eligible Matched “BUTYLATED HYDROXYANISOLE” with food-use authorization under 172.110, 172.115, 172.185, 172.515 — matched by name, not a shared regulatory number. |
| 321 | Butylated hydroxytoluene Synonyms: BHT | Antioxidant | EFSA ADI: = 0.25 mg/kg bw/day Based on the NOAEL of 25 mg/kg bw/day, derived from both new 2-generation studies, and an uncertainty factor of 100 the Panel established an ADI for BHT of 0.25 mg/kg bw. The NOAEL of 25 mg/kg bw/day for the reproductive effects is below the BMDL10 value of 247 mg/kg bw/day derived by the Panel from the data of Olsen et al. for the incidence of hepatocellular carcinoma in male rats. The Panel concluded that this NOAEL of 25 mg/kg bw/day also covers the hepatocellular carcinomas observed in the long term studies with BHT. EFSA source ↗ | Eligible | Eligible Matched “BUTYLATED HYDROXYTOLUENE” with food-use authorization under 172.110, 172.115, 172.185, 172.615 — matched by name, not a shared regulatory number. |
| 322 | Lecithins | Antioxidant, Emulsifier | — | Eligible | Eligible Matched “LECITHIN” with food-use authorization under 175.300, 176.170, 184.1400 — matched by name, not a shared regulatory number. |
| 323 | Anoxomer | Antioxidant | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “ANOXOMER” with food-use authorization under 172.105 — matched by name, not a shared regulatory number. | |
| 324 | Ethoxyquin | Antioxidant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “ETHOXYQUIN” with food-use authorization under 73.275, 73.295, 172.140, 177.2600 — matched by name, not a shared regulatory number. |
| 325 | Sodium lactate | Acidity regulator, Antioxidant, Bulking agent, Emulsifier, Emulsifying salt, Humectant, Thickener | JECFA (WHO/FAO) NOT LIMITED(1974) Neither D(-)-lactic acid nor DL-lactic acid should be used in infant foods JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM LACTATE” with food-use authorization under 184.1768 — matched by name, not a shared regulatory number. |
| 326 | Potassium lactate | Acidity regulator, Antioxidant, Emulsifier, Humectant | JECFA (WHO/FAO) NOT LIMITED(1974) Neither D(-)-lactic acid nor DL-lactic acid should be used in infant foods JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POTASSIUM LACTATE” with food-use authorization under 184.1639 — matched by name, not a shared regulatory number. |
| 327 | Calcium lactate | Acidity regulator, Emulsifying salt, Firming agent, Flour treatment agent, Thickener | JECFA (WHO/FAO) NOT LIMITED(1974) Neither D(-)-lactic acid nor DL-lactic acid should be used in infant foods JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CALCIUM LACTATE” with food-use authorization under 184.1207 — matched by name, not a shared regulatory number. |
| 328 | Ammonium lactate | Acidity regulator, Flour treatment agent | JECFA (WHO/FAO) NOT LIMITED(1973) Neither D(-)-lactic acid nor DL-lactic acid should be used in infant foods JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 329 | Magnesium lactate, DL- | Acidity regulator, Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 330 | Citric acid | Acidity regulator, Antioxidant, Colour retention agent, Sequestrant | Eligible | Eligible Matched “CITRIC ACID” with food-use authorization under 73.85, 172.755, 172.861, 173.160 — matched by name, not a shared regulatory number. | |
| 331 | Sodium citrates | Acidity regulator, Emulsifier, Emulsifying salt, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 332 | Potassium citrates | Acidity regulator, Emulsifying salt, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 333 | Calcium citrates | Acidity regulator, Firming agent, Emulsifying salt, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 334 | Tartaric acid, L(+)- | Acidity regulator, Antioxidant, Flavour enhancer, Sequestrant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 335 | Sodium tartrates | Acidity regulator, Emulsifying salt, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 336 | Potassium tartrates | Acidity regulator, Emulsifying salt, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 337 | Potassium sodium L(+)-tartrate Synonyms: Rochelle salt, Seignette salt, Potassium sodium dextro-tartrate | Acidity regulator, Emulsifying salt, Sequestrant, Stabilizer | Eligible | Eligible Matched “SODIUM POTASSIUM TARTRATE” with food-use authorization under 184.1804 — matched by name, not a shared regulatory number. | |
| 338 | Phosphoric acid Synonyms: Orthophosphoric acid | Acidity regulator, Antioxidant, Sequestrant | Eligible | Eligible Matched “PHOSPHORIC ACID” with food-use authorization under 73.275, 73.85, 175.300, 177.2260 — matched by name, not a shared regulatory number. | |
| 339 | Sodium phosphates | Acidity regulator, Emulsifier, Emulsifying salt, Humectant, Raising agent, Sequestrant, Stabilizer, Thickener, Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 340 | Potassium phosphates | Acidity regulator, Emulsifier, Emulsifying salt, Humectant, Sequestrant, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 341 | Calcium phosphates | Acidity regulator, Anticaking agent, Emulsifying salt, Firming agent, Flour treatment agent, Humectant, Raising agent, Sequestrant, Stabilizer, Thickener, Emulsifier | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 342 | Ammonium phosphates | Acidity regulator, Flour treatment agent, Raising agent, Thickener, Stabilizer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 343 | Magnesium phosphates | Acidity regulator, Anticaking agent, Emulsifying salt, Stabilizer, Thickener, Raising agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 344 | Lecithin citrate | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 345 | Magnesium citrate | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 349 | Ammonium malate | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 350 | Sodium malates | Acidity regulator, Humectant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 351 | Potassium malates | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 352 | Calcium malates | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 353 | Metatartaric acid | Acidity regulator, Emulsifier, Stabilizer, Thickener | EFSA ADI (group): = 240 mg/kg bw/day Based on the presumption that metatartaric acid is fully hydrolysed presystemically to L(+)-tartaric acid, the Panel concluded that metatartaric acid (E 353) should be included in the group acceptable daily intake (ADI) of 240 mg/kg body weight (bw) per day, expressed as tartaric acid, for L(+)-tartaric acid-tartrates (E 334-337, 354) which was established by the EFSA FAF Panel in 2020. The Panel also concluded that there is no safety concern for the use of metatartaric acid (E 353) at the reported use and use level. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 354 | Calcium tartrate, DL- | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 355 | Adipic acid | Acidity regulator | Eligible | Eligible Matched “ADIPIC ACID” with food-use authorization under 175.300, 175.320, 176.170, 176.180 — matched by name, not a shared regulatory number. | |
| 356 | Sodium adipates | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 357 | Potassium adipates | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 359 | Ammonium adipates | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 363 | Succinic acid | Acidity regulator | — | Eligible | Eligible Matched “SUCCINIC ACID” with food-use authorization under 172.861, 184.1091 — matched by name, not a shared regulatory number. |
| 364 | Sodium succinates | Acidity regulator, Flavour enhancer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 365 | Sodium fumarates | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 366 | Potassium fumarates | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 367 | Calcium fumarates | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 368 | Ammonium fumarate | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 370 | Heptonolactone, 1,4- | Acidity regulator, Sequestrant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 375 | Nicotinic acid | Colour retention agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “NIACIN” with food-use authorization under 184.1530 — matched by name, not a shared regulatory number. |
| 380 | Triammonium citrate Synonyms: Citric acid triammonium salt, Ammonium citrate tribasic | Acidity regulator | JECFA (WHO/FAO) NOT LIMITED(1979) Included in the ADI for citric acid and bases JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 381 | Ferric ammonium citrate Synonyms: AMMONIUM IRON (III) CITRATE, AMMONIUM IRON CITRATE, AMMONIUM FERRIC CITRATE, IRON AMMONIUM CITRATE | Anticaking agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “IRON AMMONIUM CITRATE” with food-use authorization under 172.430, 182.20, 184.1296 — matched by name, not a shared regulatory number. |
| 383 | Calcium glycerophosphate | Gelling agent, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CALCIUM GLYCEROPHOSPHATE” with food-use authorization under 175.300, 181.29, 184.1201 — matched by name, not a shared regulatory number. |
| 384 | Isopropyl citrates | Antioxidant, Preservative, Sequestrant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 385 | Calcium disodium ethylenediaminetetraacetate Synonyms: CALCIUM DISODIUM EDTA, CALCIUM DISODIUM EDETATE | Antioxidant, Colour retention agent, Preservative, Sequestrant | JECFA (WHO/FAO) 0-2.5 mg/kg bw(1973) As calcium disodium EDTA; no excess of disodium EDTA should remain in foods JECFA (WHO/FAO) source ↗EFSA ADI: = 2.5 mg/kg bw/day JECFA established an ADI for calcium disodium EDTA of 2.5 mg/kg bw/day, which can be calculated to amount to 1.9 mg EDTA/kg bw/day (JEFCA, 1996). EFSA source ↗ | Eligible | Eligible Matched “EDTA, CALCIUM DISODIUM” with food-use authorization under 73.1, 172.120, 172.135, 175.105 — matched by name, not a shared regulatory number. |
| 386 | Disodium ethylenediaminetetraacetate Synonyms: Disodium edta, Disodium edetate | Antioxidant, Colour retention agent, Stabilizer, Preservative, Sequestrant | JECFA (WHO/FAO) 0-2.5 mg/kg bw(1973) As calcium disodium EDTA; no excess disodium EDTA to remain in foods JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “EDTA, DISODIUM” with food-use authorization under 73.1, 172.120, 172.135, 175.105 — matched by name, not a shared regulatory number. |
| 387 | Oxystearin | Antioxidant, Sequestrant | JECFA (WHO/FAO) WITHDRAWN (2001)(1973) The ADI of 0-25 mg/kg bw that was established at the seventeenth meeting (1973) was withdrawn at the fifty-seventh meeting (2001) following the Committee's decision to withdraw the specifications due to lack of commercial use of the additive; see TRS 909/44 JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “OXYSTEARIN” with food-use authorization under 172.818, 173.340, 176.170 — matched by name, not a shared regulatory number. |
| 388 | Thiodipropionic acid | Antioxidant | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “THIODIPROPIONIC ACID” with food-use authorization under 175.300, 177.1010, 178.2010, 181.24 — matched by name, not a shared regulatory number. | |
| 389 | Dilauryl thiodipropionate | Antioxidant | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “DILAURYL THIODIPROPIONATE” with food-use authorization under 175.300, 177.1010, 181.24, 182.3280 — matched by name, not a shared regulatory number. | |
| 390 | Distearyl thiodipropionate | Antioxidant | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 391 | Phytic acid | Preservative | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 392 | Rosemary extract Synonyms: Carnosic acid | Antioxidant | JECFA (WHO/FAO) 0–0.6 mg/kg bw (expressed as carnosic acid and carnosol)(2025) A BMDL20 of 97 mg/kg bw per day expressed as carnosic acid plus carnosol was calculated for a new study on thyroid hormone levels in rat pups from dams treated with rosemary extract in the diet during pregnancy and lactation. This BMDL20 is higher than the NOAEL of 64 mg/kg bw per day, expressed as carnosic acid plus carnosol, on which the current temporary ADI for rosemary extract is based. In the derivation of the temporary ADI of 0–0.3 mg/kg bw per day, an additional uncertainty factor of 2 was incorporated into the overall uncertainty factor of 200 to account for the absence of studies to elucidate the potential developmental and reproductive toxicity of rosemary extract. This factor is no longer necessary. The temporary ADI of 0–0.3 mg/kg bw per day (expressed as carnosic acid and carnosol) was therefore withdrawn and an ADI of 0–0.6 mg/kg bw per day (expressed as carnosic acid and carnosol) was established. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “ROSEMARY, EXTRACT (ROSMARINUS OFFICINALIS L.)” with food-use authorization under 182.20 — matched by name, not a shared regulatory number. |
| 399 | Calcium lactobionate | Stabilizer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CALCIUM LACTOBIONATE” with food-use authorization under 172.720 — matched by name, not a shared regulatory number. |
| 400 | Alginic acid | Bulking agent, Carrier, Emulsifier, Foaming agent, Gelling agent, Glazing agent, Humectant, Sequestrant, Stabilizer, Thickener | Eligible | Eligible Matched “ALGINIC ACID” with food-use authorization under 184.1011 — matched by name, not a shared regulatory number. | |
| 401 | Sodium alginate | Bulking agent, Carrier, Emulsifier, Foaming agent, Gelling agent, Glazing agent, Humectant, Sequestrant, Stabilizer, Thickener | Eligible | Eligible Matched “ALGINATE, SODIUM” with food-use authorization under 173.310, 184.1724 — matched by name, not a shared regulatory number. | |
| 402 | Potassium alginate | Bulking agent, Carrier, Emulsifier, Foaming agent, Gelling agent, Glazing agent, Humectant, Sequestrant, Stabilizer, Thickener | Eligible | Eligible Matched “ALGINATE, POTASSIUM” with food-use authorization under 184.1610 — matched by name, not a shared regulatory number. | |
| 403 | Ammonium alginate | Bulking agent, Carrier, Emulsifier, Foaming agent, Gelling agent, Glazing agent, Humectant, Sequestrant, Stabilizer, Thickener | Eligible | Eligible Matched “ALGINATE, AMMONIUM” with food-use authorization under 173.310, 178.3900, 184.1133 — matched by name, not a shared regulatory number. | |
| 404 | Calcium alginate | Antifoaming agent, Bulking agent, Carrier, Gelling agent, Glazing agent, Humectant, Sequestrant, Stabilizer, Thickener | Eligible | Eligible Matched “ALGINATE, CALCIUM” with food-use authorization under 184.1187 — matched by name, not a shared regulatory number. | |
| 405 | Propylene glycol alginate Synonyms: 1,2-Propane-diol ester of alginic acid, Hydroxypropyl alginate, Propane 1,2-diol alginate | Bulking agent, Carrier, Emulsifier, Foaming agent, Gelling agent, Stabilizer, Thickener | Eligible | Eligible Matched “PROPYLENE GLYCOL ALGINATE” with food-use authorization under 172.210, 172.858, 173.340, 176.170 — matched by name, not a shared regulatory number. | |
| 406 | Agar Synonyms: AGAR-AGAR, JAPAN AGAR, BENGAL, CEYLON, CHINESE OR JAPANESE ISINGLASS, LAYOR CARANG, GELOSE | Bulking agent, Carrier, Emulsifier, Glazing agent, Gelling agent, Humectant, Stabilizer, Thickener | Eligible | Eligible Matched “AGAR (GELIDIUM SPP.)” with food-use authorization under 184.1115 — matched by name, not a shared regulatory number. | |
| 407 | Carrageenan Synonyms: Irish moss gelose (from chondrus ssp.), Eucheuman (from Eucheuma Spp.), Iridophycan (from Iridaea Spp.), Furcellaran or Danish agar (from Furcellaria Fastigiata), Hypnean (from Hypnea Spp.) | Bulking agent, Carrier, Emulsifier, Gelling agent, Glazing agent, Humectant, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2014) JECFA reviewed data published since the sixty-eighth meeting in 2007, focusing in particular on data of relevance to the safety assessment of the use of carrageenan (but not processed Eucheuma seaweed) in infant formula. [...] JECFA concluded that the use of carrageenan in infant formula or formula for special medical purposes at concentrations up to 1000 mg/L is not of concern. JECFA recognized that there is variability in medical conditions among infants requiring formulas for special medical purposes that contain the higher levels of carrageenan, and JECFA noted that these infants would normally be under medical supervision. JECFA (WHO/FAO) source ↗EFSA ADI (group): = 75 mg/kg bw/day The Panel noted uncertainties as regards the chemistry, the exposure assessment and biological and toxicological data. Overall, taking into account the lack of adequate data to address these uncertainties, the Panel concluded that the existing group ADI for carrageenan (E 407) and processed Eucheuma seaweed (E 407a) of 75 mg/kg bw per day should be considered temporary, whilst the database should be improved within 5 years after publication of this opinion. Within the given time frame, high importance should be ascribed to the establishment of an adequate interlaboratory validated analytical method to quantify, at the existing 5% limit, the low weight-average molecular weight fraction of carrageenan, and to establish whether or not this fraction is associated with health risks. The Panel further concluded that in the refined brand-loyal exposure assessment scenario the exposure estimates exceeded, in some cases by up to approximately 10-fold, the temporary existing ADI at the high level (95th percentile) for all population groups and at the mean for all population groups except for infants and the elderly. Although the exposure may be overestimated the extent of the exceedance of the ADI (10-fold) may be a safety concern. EFSA source ↗ | Eligible | Eligible Matched “CARRAGEENAN” with food-use authorization under 172.620, 172.625, 182.7255 — matched by name, not a shared regulatory number. |
| 407a | Processed euchema seaweed (PES) | Bulking agent, Carrier, Emulsifier, Gelling agent, Glazing agent, Humectant, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 408 | Bakers yeast glycan | Gelling agent, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “BAKER'S YEAST GLYCAN” with food-use authorization under 172.898 — matched by name, not a shared regulatory number. |
| 409 | Arabinogalactan | Gelling agent, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “ARABINOGALACTAN” with food-use authorization under 172.230, 172.610 — matched by name, not a shared regulatory number. |
| 410 | Carob bean gum Synonyms: Locust bean gum, carob gum, Carob bean gum (clarified) | Emulsifier, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2025) Only considered whether its safe for use in infant formulas. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “LOCUST (CAROB) BEAN GUM” with food-use authorization under 182.20, 184.1343, 186.1343, 240.1051 — matched by name, not a shared regulatory number. |
| 411 | Oat gum | Stabilizer, Thickener | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “OAT GUM” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. | |
| 412 | Guar gum Synonyms: GUAR FLOUR, GUM CYAMOPSIS, GUAR GUM (CLARIFIED) | Emulsifier, Stabilizer, Thickener | Eligible | Eligible Matched “GUAR, GUM (CYAMOPSIS TETRAGONOLOBUS (L.))” with food-use authorization under 184.1339 — matched by name, not a shared regulatory number. | |
| 413 | Tragacanth gum | Emulsifier, Stabilizer, Thickener | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 414 | Gum arabic (Acacia gum) | Bulking agent, Carrier, Emulsifier, Glazing agent, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 415 | Xanthan gum | Emulsifier, Foaming agent, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2016) A NOAEL of 750 mg/kg bw per day was established for xanthan gum in neonatal pigs, which are an appropriate animal model for the assessment of the safety of the additive for infants. The margin of exposure based on this NOAEL and the conservative estimate of xanthan gum intake of 220 mg/kg bw per day by infants (high energy requirements for fully formula-fed infants) is 3.4. On the basis of a number of considerations, JECFA concluded that the consumption of xanthan gum in infant formula or formula for special medical purposes intended for infants is of no safety concern at the maximum proposed use level of 1000 mg/L. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “XANTHAN GUM” with food-use authorization under 172.695, 176.170, 177.1350 — matched by name, not a shared regulatory number. |
| 416 | Karaya gum Synonyms: Karaya, Gum sterculia, Sterculia, Kadaya, Katilo, Kullo, Kuterra, Gum karaya | Emulsifier, Stabilizer, Thickener | Eligible | Eligible Matched “KARAYA, GUM (STERCULIA URENS ROXB.)” with food-use authorization under 184.1349 — matched by name, not a shared regulatory number. | |
| 417 | Tara gum Synonyms: Peruvian carob | Gelling agent, Stabilizer, Thickener | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 418 | Gellan gum | Stabilizer, Thickener | Eligible | Eligible Matched “GELLAN GUM” with food-use authorization under 172.665 — matched by name, not a shared regulatory number. | |
| 419 | Gum ghatti Synonyms: Indian gum, Gum ghati, Ghatti gum | Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “GHATTI, GUM (ANOGEISSUS LATIFOLIA WALL.)” with food-use authorization under 184.1333 — matched by name, not a shared regulatory number. |
| 420 | Sorbitols | Bulking agent, Humectant, Sequestrant, Stabilizer, Sweetener, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 421 | Mannitol Synonyms: D-Mannitol, Mannite | Anticaking agent, Bulking agent, Humectant, Stabilizer, Sweetener, Thickener | Eligible | Not listed Matched “MANNITOL” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. | |
| 422 | Glycerol Synonyms: Glycerin | Humectant, Thickener | JECFA (WHO/FAO) NOT SPECIFIED (1976)(2002) Evaluation not finalized, pending definition of "flavouring agent" JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “GLYCERIN” with food-use authorization under 172.811, 175.300, 175.320, 176.210 — matched by name, not a shared regulatory number. |
| 423 | Octenyl succinic acid (OSA) modified gum arabic Synonyms: Gum arabic hydrogen octenylbutandioate, Gum arabic hydrogen octenylsuccinate, OSA modified gum arabic, OSA modified gum acacia | Emulsifier | JECFA (WHO/FAO) NOT SPECIFIED(2016) The Committee removed the temporary designatione and established an ADI “not specified” for OSAmodified gum arabic. The Committee confirmed the validity of the dietary exposure estimate for risk assessment purposes set at a previous meeting. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 424 | Curdlan Synonyms: beta-1,3-Glucan | Firming agent, Gelling agent, Stabilizer, Thickener | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CURDLAN” with food-use authorization under 172.809 — matched by name, not a shared regulatory number. | |
| 425 | Konjac flour Synonyms: Konjac mannan, Konjac, Konnyaku | Carrier, Emulsifier, Gelling agent, Glazing agent, Humectant, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(1996) Includes uses as a thickener, emulsifier, stabilizer, and gelling, texturizing and glazing agent. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 426 | Soybean hemicellulose | Anticaking agent, Emulsifier, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 427 | Cassia gum | Emulsifier, Gelling agent, Stabilizer, Thickener | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 428 | Gelatin Synonyms: Gelatin edible | Carrier, Emulsifier, Gelling agent, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “GELATIN” with food-use authorization under 172.230, 172.255, 172.280, 182.70 — matched by name, not a shared regulatory number. |
| 429 | Peptones | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “PEPTONES” with food-use authorization under 184.1553 — matched by name, not a shared regulatory number. |
| 430 | Polyoxyethylene (8) stearate Synonyms: POLYOXYL (8) STEARATE | Emulsifier | JECFA (WHO/FAO) 0-25 mg/kg bw(1973) As total of polyoxyethylene (8) and (40) stearates JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 431 | Polyoxyethylene (40) stearate Synonyms: Polyoxyl (40) stearate, Polyoxyethylene (40) monostearate | Emulsifier | JECFA (WHO/FAO) 0-25 mg/kg bw(1973) As total of polyoxyethylene (8) and (40) stearates JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 432 | Polyoxyethylene (20) sorbitan monolaurate Synonyms: POLYSORBATE 20 | Emulsifier, Stabilizer | JECFA (WHO/FAO) Group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) JECFA considered that the toxicological data reviewed support the previously identified NOAEL of 2500 mg/kg bw per day, the highest dose tested in two long-term toxicity studies in rats, used to establish the group ADI of 0–25 mg/kg bw for the polysorbates. JECFA therefore confirmed the group ADI of 0–25 mg/kg bw for the polyoxyethylene (20) sorbitan monoesters of lauric, oleic, palmitic and stearic acid and the triester of stearic acid. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POLYSORBATE 20” with food-use authorization under 172.515, 173.310, 175.105, 178.3400 — matched by name, not a shared regulatory number. |
| 433 | Polyoxyethylene (20) sorbitan monooleate Synonyms: Polysorbate 80 | Emulsifier, Stabilizer | JECFA (WHO/FAO) Group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) JECFA considered that the toxicological data reviewed support the previously identified NOAEL of 2500 mg/kg bw per day, the highest dose tested in two long-term toxicity studies in rats, used to establish the group ADI of 0–25 mg/kg bw for the polysorbates. JECFA therefore confirmed the group ADI of 0–25 mg/kg bw for the polyoxyethylene (20) sorbitan monoesters of lauric, oleic, palmitic and stearic acid and the triester of stearic acid. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POLYSORBATE 80” with food-use authorization under 73.1, 73.1001, 172.515, 172.836 — matched by name, not a shared regulatory number. |
| 434 | Polyoxyethylene (20) sorbitan monopalmitate Synonyms: Polysorbate 40 | Emulsifier | JECFA (WHO/FAO) Group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) JECFA considered that the toxicological data reviewed support the previously identified NOAEL of 2500 mg/kg bw per day, the highest dose tested in two long-term toxicity studies in rats, used to establish the group ADI of 0–25 mg/kg bw for the polysorbates. JECFA therefore confirmed the group ADI of 0–25 mg/kg bw for the polyoxyethylene (20) sorbitan monoesters of lauric, oleic, palmitic and stearic acid and the triester of stearic acid. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 435 | Polyoxyethylene (20) sorbitan monostearate Synonyms: Polysorbate 60 | Emulsifier, Stabilizer | JECFA (WHO/FAO) Group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) JECFA considered that the toxicological data reviewed support the previously identified NOAEL of 2500 mg/kg bw per day, the highest dose tested in two long-term toxicity studies in rats, used to establish the group ADI of 0–25 mg/kg bw for the polysorbates. JECFA therefore confirmed the group ADI of 0–25 mg/kg bw for the polyoxyethylene (20) sorbitan monoesters of lauric, oleic, palmitic and stearic acid and the triester of stearic acid. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POLYSORBATE 60” with food-use authorization under 73.1001, 172.515, 172.836, 172.838 — matched by name, not a shared regulatory number. |
| 436 | Polyoxyethylene (20) sorbitan tristearate Synonyms: POLYSORBATE 65 | Emulsifier, Stabilizer | JECFA (WHO/FAO) Group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) JECFA considered that the toxicological data reviewed support the previously identified NOAEL of 2500 mg/kg bw per day, the highest dose tested in two long-term toxicity studies in rats, used to establish the group ADI of 0–25 mg/kg bw for the polysorbates. JECFA therefore confirmed the group ADI of 0–25 mg/kg bw for the polyoxyethylene (20) sorbitan monoesters of lauric, oleic, palmitic and stearic acid and the triester of stearic acid. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POLYSORBATE 65” with food-use authorization under 73.1001, 172.836, 172.838, 172.840 — matched by name, not a shared regulatory number. |
| 440 | Pectins | Emulsifier, Gelling agent, Glazing agent, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2016) The No-Observed-Adverse-Effect level (NOAEL) in a previously evaluated neonatal pig study was recalculated to be 1049 mg/kg bw per day using measured concentrations of pectin in milk replacer rather than target concentrations. At the new maximum proposed use level of 0.2%, the estimated exposure of infants 0–12 weeks of age would be up to 360 and 440 mg/kg bw per day at mean and high consumption. The margins of exposure for average and high consumers are 2.9 and 2.4, respectively, when compared with the NOAEL of 1049 mg/kg bw per day. On the basis of a number of considerations, the Committee concluded that the margins of exposure calculated for the use of pectin at 0.2% in infant formula indicate low risk for the health of infants and are not of concern. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 441 | Superglycerinated hydrogenated rapeseed oil | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “RAPESEED OIL, HYDROGENATED, SUPERGLYCERINATED” with food-use authorization under 184.1555 — matched by name, not a shared regulatory number. |
| 442 | Ammonium salts of phosphatidic acid Synonyms: Ammonium phosphatides, Emulsifier YN, Mixed ammonium salts of phosphorylated glycerides | Emulsifier | JECFA (WHO/FAO) 0-30 mg/kg bw(1974) The phosphorus content is to be included in the ADI for phosphates JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 443 | Brominated vegetable oils Synonyms: Brominated oils | Emulsifier, Stabilizer | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 444 | Sucrose acetate isobutyrate Synonyms: SAIB | Emulsifier, Stabilizer | EFSA ADI: = 20 mg/kg bw/day The Panel concluded that the present data set on absorption, distribution, metabolism and excretion, genotoxicity, subchronic, developmental and long-term toxicity, and carcinogenicity give reason to revise the ADI of 10 mg/kg bw per day allocated by the SCF in 1994 to 20 mg/kg bw per day. EFSA source ↗ | Eligible | Eligible Matched “SUCROSE ACETATE ISOBUTYRATE” with food-use authorization under 172.833, 175.105 — matched by name, not a shared regulatory number. |
| 445 | Glycerol esters of rosin | Emulsifier, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 446 | Succistearin | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “SUCCISTEARIN” with food-use authorization under 172.765 — matched by name, not a shared regulatory number. |
| 450 | Diphosphates | Acidity regulator, Emulsifier, Emulsifying salt, Humectant, Raising agent, Sequestrant, Stabilizer, Thickener, Firming agent, Flour treatment agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 451 | Triphosphates | Acidity regulator, Emulsifier, Emulsifying salt, Humectant, Sequestrant, Stabilizer, Thickener, Raising agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 452 | Polyphosphates | Acidity regulator, Emulsifier, Emulsifying salt, Humectant, Raising agent, Sequestrant, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 453 | Ferric(III)-orthophosphate | Colour, Carrier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 454 | Ferric(III)-pyrophosphate | Carrier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 455 | Yeast mannoproteins | Stabilizer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 457 | Cyclodextrin, alpha- | Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 458 | Cyclodextrin, gamma- | Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 459 | Cyclodextrin, beta- | Carrier, Stabilizer, Thickener | — | Eligible | Not listed Matched “BETA-CYCLODEXTRIN” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 460 | Celluloses | Anticaking agent, Bulking agent, Carrier, Glazing agent, Emulsifier, Foaming agent, Stabilizer, Thickener, Humectant | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 461 | Methyl cellulose Synonyms: Cellulose methyl ether | Bulking agent, Glazing agent, Emulsifier, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(1989) Group ADI for modified celluloses: ethyl cellulose, ethyl hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, methyl ethyl cellulose, and sodium carboxymethyl cellulose JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CELLULOSE, METHYL” with food-use authorization under 175.105, 175.210, 175.300, 176.200 — matched by name, not a shared regulatory number. |
| 462 | Ethyl cellulose Binder binder | Bulking agent, Carrier, Glazing agent, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 463 | Hydroxypropyl cellulose Synonyms: Cellulose hydroxypropyl ether, Modified cellulose | Emulsifier, Foaming agent, Glazing agent, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(1989) Group ADI for modified celluloses: ethyl cellulose, ethyl hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, methyl ethyl cellulose, and sodium carboxymethyl cellulose. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “HYDROXYPROPYL CELLULOSE” with food-use authorization under 73.1001, 172.870, 177.1200 — matched by name, not a shared regulatory number. |
| 464 | Hydroxypropyl methyl cellulose | Bulking agent, Glazing agent, Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “HYDROXYPROPYL METHYLCELLULOSE” with food-use authorization under 172.874, 175.105, 175.300, 177.1960 — matched by name, not a shared regulatory number. |
| 465 | Methyl ethyl cellulose Synonyms: MEC | Emulsifier, Foaming agent, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(1989) Group ADI for modified celluloses: ethyl cellulose, ethyl hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, methyl ethyl cellulose, and sodium carboxymethyl cellulose JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CELLULOSE, METHYL ETHYL” with food-use authorization under 172.872 — matched by name, not a shared regulatory number. |
| 466 | Sodium carboxymethyl cellulose (Cellulose gum) | Bulking agent, Emulsifier, Firming agent, Gelling agent, Glazing agent, Humectant, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 467 | Ethyl hydroxyethyl cellulose | Emulsifier, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(1989) Group ADI for modified celluloses: ethyl cellulose, ethyl hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, methyl ethyl cellulose, and sodium carboxymethyl cellulose JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 468 | Cross-linked sodium carboxymethyl cellulose (Cross-linked cellulose gum) | Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 469 | Sodium carboxymethyl cellulose, enzymatically hydrolysed (Cellulose gum, enzymatically hydrolyzed) | Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 470 | Salts of fatty acids, with base aluminium, ammonium, calcium, magnesium, potassium, sodium | Anticaking agent, Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 471 | Mono- and di- glycerides of fatty acids | Antifoaming agent, Emulsifier, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 472a | Acetic and fatty acid esters of glycerol Synonyms: Acetic acid esters of mono- and diglycerides, Acetoglycerides, Acetylated mono- and diglycerides | Emulsifier, Sequestrant, Stabilizer | JECFA (WHO/FAO) NOT LIMITED(1973) As sum of total glycerol esters of fatty acids and acetic, citric, lactic and tartaric acids, provided that the total food additive intake of tartaric acid does not exceed 30 mg/kg. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 472b | Lactic and fatty acid esters of glycerol Synonyms: Lactic acid esters of mono- and diglycerides, Lactoglycerides | Emulsifier, Sequestrant, Stabilizer | JECFA (WHO/FAO) NOT LIMITED(1973) As sum of total glycerol esters of fatty acids and acetic, citric, lactic and tartaric acids, provided that the total food additive intake of tartaric acid does not exceed 30 mg/kg JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 472c | Citric and fatty acid esters of glycerol Synonyms: Citric acid esters of mono- and di-glycerides, Citroglycerides, Citrem | Antioxidant, Emulsifier, Flour treatment agent, Sequestrant, Stabilizer | Eligible | Not listed Matched “CITRIC AND FATTY ACID ESTERS OF GLYCEROL” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. | |
| 472e | Diacetyltartaric and fatty acid esters of glycerol Synonyms: INS No. 472e: Diacetyltartaric acid esters of mono- and diglycerides, datem, INS No. 472f: Tartaric, acetic and fatty acid esters of glycerol, mixed, Mixed acetic and tartaric acid esters of mono- and diglycerides of fatty acid | Emulsifier, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 472d | Tartaric acid esters of mono- and di- glycerides of fatty acids | Emulsifier, Sequestrant, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 472g | Succinylated monoglycerides | Emulsifier, Sequestrant, Stabilizer | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “SUCCINYLATED MONOGLYCERIDES” with food-use authorization under 172.830 — matched by name, not a shared regulatory number. | |
| 473 | Sucrose esters of fatty acids Synonyms: Sucrose fatty acid esters | Emulsifier, Foaming agent, Glazing agent, Stabilizer | EFSA ADI (group): = 40 mg/kg bw/day The ADI of 40 mg/kg bw/day for sucrose esters of fatty acids (E 473) and sucroglycerides (E 474) has been established by EFSA in 2004. The Panel noted that the current intake of sucrose esters of fatty acids is considerably lower than previously estimated (EFSA 2010), but is still above this ADI (established by EFSA in 2004) for children high level consumers. However, an intake resulting from its use as a surface treatment for fruits and the additional proposed use in clear flavoured soft drinks contributes to 0.25% and 0.1% of the ADI, respectively. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 473a | Sucrose oligoesters, type I and type II | Emulsifier, Glazing agent, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 474 | Sucroglycerides | Emulsifier | JECFA (WHO/FAO) 0-30 mg/kg bw(1997) Group ADI for sucrose esters of fatty acids and sucroglycerides JECFA (WHO/FAO) source ↗EFSA ADI (group): = 40 mg/kg bw/day The ADI of 40 mg/kg bw/day for sucrose esters of fatty acids (E 473) and sucroglycerides (E 474) has been established by EFSA in 2004. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 475 | Polyglycerol esters of fatty acids Synonyms: Glycerin fatty acid esters | Emulsifier, Stabilizer | JECFA (WHO/FAO) 0-25 mg/kg bw(2024) At its Seventeenth meeting, JECFA established an ADI of 0–25 mg/kg bw for Polyglycerol esters of fatty acids, based on a long-term study in rats in which there were no effects at 2500 mg/kg bw, the highest dose tested. In the absence of any new toxicological information, JECFA re-affirmed the ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POLYGLYCEROL ESTERS OF FATTY ACIDS” with food-use authorization under 73.85, 172.854 — matched by name, not a shared regulatory number. |
| 476 | Polyglycerol esters of interesterified ricinoleic acid Synonyms: Glycerin esters of condensed castor oil fatty acids, polyglycerol esters of polycondensed fatty acids from castor oil | Emulsifier | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 477 | Propylene glycol esters of fatty acids Synonyms: Propane-1,2-diol esters of fatty acids | Emulsifier | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 478 | Lactylated fatty acid esters of glycerol and propylene glycol | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “LACTYLATED FATTY ACID ESTERS OF GLYCEROL AND PROPYLENE GLYCOL” with food-use authorization under 172.850 — matched by name, not a shared regulatory number. |
| 479 | Thermally oxidized soya bean oil interacted with mono- and diglycerides of fatty acids Synonyms: TOSOM | Emulsifier | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 480 | Dioctyl sodium sulfosuccinate Synonyms: DSS, Docusate sodium | Emulsifier, Humectant | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “DIOCTYL SODIUM SULFOSUCCINATE” with food-use authorization under 73.1, 172.520, 172.808, 172.810 — matched by name, not a shared regulatory number. | |
| 481 | Sodium lactylates | Flour treatment agent, Emulsifier, Foaming agent, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 482 | Calcium lactylates | Emulsifier, Flour treatment agent, Foaming agent, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 483 | Stearyl tartrate Synonyms: Stearyl palmityl tartrate | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 484 | Stearyl citrate | Antioxidant, Emulsifier, Sequestrant | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “STEARYL CITRATE” with food-use authorization under 184.1851 — matched by name, not a shared regulatory number. | |
| 485 | Sodium stearoyl fumarate | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 486 | Calcium stearoyl fumarate | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 487 | Sodium laurylsulfate | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 488 | Ethoxylated mono- and di-glycerides | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 489 | Methyl glucoside-coconut oil ester | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “METHYL GLUCOSIDE-COCONUT OIL ESTER” with food-use authorization under 172.816, 178.3600 — matched by name, not a shared regulatory number. |
| 491 | Sorbitan monostearate | Emulsifier | JECFA (WHO/FAO) Temporary group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) The previous JECFA derived a group ADI of 0–25 mg/kg bw for the sum of sorbitan fatty acid esters (INS No. 491–495), based on the NOAEL of 2500 mg/kg bw per day and applying an uncertainty factor of 100. However, the genotoxicity studies available to the current JECFA provided an indication of the clastogenic effects of sorbitan monostearate, requiring further investigation. In the absence of the additional data that were available to EFSA, JECFA was not able to conclude on the potential for genotoxicity and withdrew the group ADI of 0–25 mg/kg bw, establishing a temporary group ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI (group): = 10 mg/kg bw/day Based on the no observed adverse effect level (NOAEL) of 2,600 mg sorbitan monostearate/kg bw per day, taking into account the ratio between the molecular weight of sorbitan monostearate (430.62 g/mol) and sorbitan (164.16 g/mol), and applying an uncertainty factor of 100, the Panel derived a group ADI of 10 mg/kg bw per day expressed as sorbitan for sorbitan esters (E 491-495) singly or in combination. This group ADI of 10 mg sorbitan/kg bw per day is equivalent to 26 mg sorbitan monostearate/kg bw per day. The Panel concluded that the exposure at the mean and the 95th percentile level, using non-brand-loyal scenario, did not exceed the ADI in any of the population groups. EFSA source ↗ | Eligible | Eligible Matched “SORBITAN MONOSTEARATE” with food-use authorization under 73.1001, 172.515, 172.836, 172.838 — matched by name, not a shared regulatory number. |
| 492 | Sorbitan tristearate | Emulsifier, Stabilizer | JECFA (WHO/FAO) Temporary group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) The previous JECFA derived a group ADI of 0–25 mg/kg bw for the sum of sorbitan fatty acid esters (INS No. 491–495), based on the NOAEL of 2500 mg/kg bw per day and applying an uncertainty factor of 100. However, the genotoxicity studies available to the current JECFA provided an indication of the clastogenic effects of sorbitan monostearate, requiring further investigation. In the absence of the additional data that were available to EFSA, JECFA was not able to conclude on the potential for genotoxicity and withdrew the group ADI of 0–25 mg/kg bw, establishing a temporary group ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI (group): = 10 mg/kg bw/day Based on the no observed adverse effect level (NOAEL) of 2,600 mg sorbitan monostearate/kg bw per day, taking into account the ratio between the molecular weight of sorbitan monostearate (430.62 g/mol) and sorbitan (164.16 g/mol), and applying an uncertainty factor of 100, the Panel derived a group ADI of 10 mg/kg bw per day expressed as sorbitan for sorbitan esters (E 491-495) singly or in combination. This group ADI of 10 mg sorbitan/kg bw per day is equivalent to 26 mg sorbitan monostearate/kg bw per day. The Panel concluded that the exposure at the mean and the 95th percentile level, using non-brand-loyal scenario, did not exceed the ADI in any of the population groups. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 493 | Sorbitan monolaurate Synonyms: Sorbitan laurate | Emulsifier, Stabilizer | JECFA (WHO/FAO) Temporary group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) The previous JECFA derived a group ADI of 0–25 mg/kg bw for the sum of sorbitan fatty acid esters (INS No. 491–495), based on the NOAEL of 2500 mg/kg bw per day and applying an uncertainty factor of 100. However, the genotoxicity studies available to the current JECFA provided an indication of the clastogenic effects of sorbitan monostearate, requiring further investigation. In the absence of the additional data that were available to EFSA, JECFA was not able to conclude on the potential for genotoxicity and withdrew the group ADI of 0–25 mg/kg bw, establishing a temporary group ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI: = 21 mg/kg bw Based on the NOAEL of 2,600 mg sorbitan monostearate/kg bw per day, taking into account the ratio between the molecular weight of sorbitan monostearate (430.62 g/mol) and sorbitan (164.16 g/mol), and applying an uncertainty factor of 100, the ANS Panel proposed a group ADI of 10 mg sorbitan/kg bw per day expressed as sorbitan for sorbitan esters (E 491-495) singly or in combination. The FEEDAP Panel calculated that the corresponding ADI for sorbitan monolaurate would be 21 mg/kg bw. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 494 | Sorbitan monooleate | Emulsifier, Stabilizer | JECFA (WHO/FAO) Temporary group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) The previous JECFA derived a group ADI of 0–25 mg/kg bw for the sum of sorbitan fatty acid esters (INS No. 491–495), based on the NOAEL of 2500 mg/kg bw per day and applying an uncertainty factor of 100. However, the genotoxicity studies available to the current JECFA provided an indication of the clastogenic effects of sorbitan monostearate, requiring further investigation. In the absence of the additional data that were available to EFSA, JECFA was not able to conclude on the potential for genotoxicity and withdrew the group ADI of 0–25 mg/kg bw, establishing a temporary group ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI (group): = 10 mg/kg bw/day Based on the no observed adverse effect level (NOAEL) of 2,600 mg sorbitan monostearate/kg bw per day, taking into account the ratio between the molecular weight of sorbitan monostearate (430.62 g/mol) and sorbitan (164.16 g/mol), and applying an uncertainty factor of 100, the Panel derived a group ADI of 10 mg/kg bw per day expressed as sorbitan for sorbitan esters (E 491-495) singly or in combination. This group ADI of 10 mg sorbitan/kg bw per day is equivalent to 26 mg sorbitan monostearate/kg bw per day. The Panel concluded that the exposure at the mean and the 95th percentile level, using non-brand-loyal scenario, did not exceed the ADI in any of the population groups. EFSA source ↗ | Eligible | Eligible Matched “SORBITAN MONOOLEATE” with food-use authorization under 73.1001, 173.75, 175.105, 178.3400 — matched by name, not a shared regulatory number. |
| 495 | Sorbitan monopalmitate | Emulsifier | JECFA (WHO/FAO) Temporary group ADI of 0-25 mg/kg bw as total polyoxyethylene (20) sorbitan esters(2026) The previous JECFA derived a group ADI of 0–25 mg/kg bw for the sum of sorbitan fatty acid esters (INS No. 491–495), based on the NOAEL of 2500 mg/kg bw per day and applying an uncertainty factor of 100. However, the genotoxicity studies available to the current JECFA provided an indication of the clastogenic effects of sorbitan monostearate, requiring further investigation. In the absence of the additional data that were available to EFSA, JECFA was not able to conclude on the potential for genotoxicity and withdrew the group ADI of 0–25 mg/kg bw, establishing a temporary group ADI of 0–25 mg/kg bw. JECFA (WHO/FAO) source ↗EFSA ADI (group): = 10 mg/kg bw/day Based on the no observed adverse effect level (NOAEL) of 2,600 mg sorbitan monostearate/kg bw per day, taking into account the ratio between the molecular weight of sorbitan monostearate (430.62 g/mol) and sorbitan (164.16 g/mol), and applying an uncertainty factor of 100, the Panel derived a group ADI of 10 mg/kg bw per day expressed as sorbitan for sorbitan esters (E 491-495) singly or in combination. This group ADI of 10 mg sorbitan/kg bw per day is equivalent to 26 mg sorbitan monostearate/kg bw per day. The Panel concluded that the exposure at the mean and the 95th percentile level, using non-brand-loyal scenario, did not exceed the ADI in any of the population groups. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 496 | Sorbitan trioleate | Stabilizer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 500 | Sodium carbonates | Acidity regulator, Anticaking agent, Raising agent, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 501 | Potassium carbonates | Acidity regulator, Stabilizer, Raising agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 503 | Ammonium carbonates | Acidity regulator, Raising agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 504 | Magnesium carbonates | Acidity regulator, Anticaking agent, Colour retention agent, Carrier | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 505 | Ferrous carbonate | Acidity regulator | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “FERROUS CARBONATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 507 | Hydrochloric acid Synonyms: Muriatic acid | Acidity regulator | Eligible | Eligible Matched “HYDROCHLORIC ACID” with food-use authorization under 172.560, 172.892, 182.1057 — matched by name, not a shared regulatory number. | |
| 508 | Potassium chloride Synonyms: Sylvine, Sylvite | Firming agent, Flavour enhancer, Stabilizer, Thickener | JECFA (WHO/FAO) NOT LIMITED(1979) Group ADI for hydrochloric acid and its magnesium, potassium and ammonium salts JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “POTASSIUM CHLORIDE” with food-use authorization under 184.1622 — matched by name, not a shared regulatory number. |
| 509 | Calcium chloride | Firming agent, Stabilizer, Thickener | Eligible | Eligible Matched “CALCIUM CHLORIDE” with food-use authorization under 172.560, 178.1010, 184.1193 — matched by name, not a shared regulatory number. | |
| 510 | Ammonium chloride Synonyms: Ammonium muriate, Sal ammoniac | Flour treatment agent | JECFA (WHO/FAO) NOT LIMITED(1979) Included in the group ADI for hydrochloric acid and its magnesium, sodium and ammonium salts JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “AMMONIUM CHLORIDE” with food-use authorization under 178.1010, 184.1138 — matched by name, not a shared regulatory number. |
| 511 | Magnesium chloride | Colour retention agent, Firming agent, Stabilizer | JECFA (WHO/FAO) NOT LIMITED(1979) Included in the ADI group for hydrochloric acid and bases JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “MAGNESIUM CHLORIDE” with food-use authorization under 172.560, 177.1650, 184.1426 — matched by name, not a shared regulatory number. |
| 512 | Stannous chloride Synonyms: Tin dichloride | Antioxidant, Colour retention agent | — | Eligible | Eligible Matched “STANNOUS CHLORIDE” with food-use authorization under 172.180, 175.300, 177.2600, 184.1845 — matched by name, not a shared regulatory number. |
| 513 | Sulfuric acid | Acidity regulator | — | Eligible | Eligible Matched “SULFURIC ACID” with food-use authorization under 73.85, 172.560, 172.892, 173.385 — matched by name, not a shared regulatory number. |
| 514 | Sodium sulfates | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 515 | Potassium sulfates | Acidity regulator | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 516 | Calcium sulfate | Acidity regulator, Firming agent, Flour treatment agent, Sequestrant, Stabilizer | Eligible | Eligible Matched “CALCIUM SULFATE” with food-use authorization under 175.300, 176.170, 178.3297, 184.1230 — matched by name, not a shared regulatory number. | |
| 517 | Ammonium sulfate | Flour treatment agent, Stabilizer | — | Eligible | Eligible Matched “AMMONIUM SULFATE” with food-use authorization under 73.85, 177.1200, 184.1143 — matched by name, not a shared regulatory number. |
| 518 | Magnesium sulfate Synonyms: EPSOM SALT (HEPTAHYDRATE) | Firming agent, Flavour enhancer | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “MAGNESIUM SULFATE” with food-use authorization under 184.1443 — matched by name, not a shared regulatory number. | |
| 519 | Cupric sulfate Synonyms: Copper sulfate, Blue stone | Colour retention agent, Preservative | JECFA (WHO/FAO) NO ADI ALLOCATED(1973) Provisional daily dietary requirement/maximum tolerable daily intake: 0.05-0.5 mg/kg body weight, expressed as Cu; See TRS 683-JECFA 26/31 (Copper) (1982) JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “COPPER SULFATE” with food-use authorization under 184.1261 — matched by name, not a shared regulatory number. |
| 520 | Aluminium sulfate | Firming agent | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 521 | Aluminium sodium sulfate Synonyms: Soda alum, Sodium alum | Acidity regulator, Firming agent | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 522 | Aluminium potassium sulfate Synonyms: Potassium alum, Potash alum, Burnt alum | Acidity regulator, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 523 | Aluminium ammonium sulfate Aciditiy regulator aciditiy regulator buffer | Colour retention agent, Firming agent, Raising agent, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 524 | Sodium hydroxide Synonyms: LYE, CAUSTIC SODA, SODIUM HYDRATE | Acidity regulator | Eligible | Eligible Matched “SODIUM HYDROXIDE” with food-use authorization under 73.85, 172.560, 172.814, 172.892 — matched by name, not a shared regulatory number. | |
| 525 | Potassium hydroxide Synonyms: Caustic potash, Potassium hydrate | Acidity regulator | Eligible | Eligible Matched “POTASSIUM HYDROXIDE” with food-use authorization under 73.85, 172.841, 175.210, 176.180 — matched by name, not a shared regulatory number. | |
| 526 | Calcium hydroxide Synonyms: Slaked lime | Acidity regulator, Firming agent | Eligible | Eligible Matched “CALCIUM HYDROXIDE” with food-use authorization under 73.85, 176.180, 176.210, 184.1205 — matched by name, not a shared regulatory number. | |
| 527 | Ammonium hydroxide Synonyms: Ammonium hydroxide, Strong ammonia solution, Aqueous ammonia | Acidity regulator | Eligible | Eligible Matched “AMMONIUM HYDROXIDE” with food-use authorization under 73.85, 177.1600, 184.1139 — matched by name, not a shared regulatory number. | |
| 528 | Magnesium hydroxide | Acidity regulator, Colour retention agent | Eligible | Eligible Matched “MAGNESIUM HYDROXIDE” with food-use authorization under 176.180, 176.210, 184.1428 — matched by name, not a shared regulatory number. | |
| 529 | Calcium oxide Synonyms: Lime | Acidity regulator, Flour treatment agent | Eligible | Eligible Matched “CALCIUM OXIDE” with food-use authorization under 184.1210 — matched by name, not a shared regulatory number. | |
| 530 | Magnesium oxide | Acidity regulator, Anticaking agent | Eligible | Eligible Matched “MAGNESIUM OXIDE” with food-use authorization under 175.300, 176.170, 177.1680, 177.2260 — matched by name, not a shared regulatory number. | |
| 535 | Sodium ferrocyanide Synonyms: YELLOW PRUSSIATE OF SODA, HEXACYANOFERRATE OF SODIUM | Anticaking agent | EFSA ADI (group): = 0.03 mg/kg bw/day In a 2-year study, animals frequently showed a higher cell excretion rate in urine samples compared to controls. Since the kidney is known to be the target organ for ferrocyanide toxicity, the Panel considered the increased cell excretion rate indicative for occasional, transient kidney toxicity and identified a NOAEL of 4.4 mg/kg bw per day. Based on this NOAEL of 4.4 mg sodium ferrocyanide/kg bw per day for male rats, the Panel derived an ADI of 0.044 mg sodium ferrocyanide/kg bw per day. Assuming that the toxicity of this compound is due to the ferrocyanide ion only, the Panel established a group ADI for sodium, potassium and calcium ferrocyanide of 0.03 mg/kg bw per day expressed as ferrocyanide ion. The Panel noted that at this ADI the potential amount of free cyanide released would not be of safety concern. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 536 | Potassium ferrocyanide Synonyms: YELLOW PRUSSIATE OF POTASH, HEXACYANOFERRATE OF POTASSIUM | Anticaking agent | EFSA ADI (group): = 0.03 mg/kg bw/day In a 2-year study, animals frequently showed a higher cell excretion rate in urine samples compared to controls. Since the kidney is known to be the target organ for ferrocyanide toxicity, the Panel considered the increased cell excretion rate indicative for occasional, transient kidney toxicity and identified a NOAEL of 4.4 mg/kg bw per day. Based on this NOAEL of 4.4 mg sodium ferrocyanide/kg bw per day for male rats, the Panel derived an ADI of 0.044 mg sodium ferrocyanide/kg bw per day. Assuming that the toxicity of this compound is due to the ferrocyanide ion only, the Panel established a group ADI for sodium, potassium and calcium ferrocyanide of 0.03 mg/kg bw per day expressed as ferrocyanide ion. The Panel noted that at this ADI the potential amount of free cyanide released would not be of safety concern. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 537 | Ferrous hexacyanomanganate | Anticaking agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 538 | Calcium ferrocyanide Synonyms: YELLOW PRUSSIATE OF LIME, HEXACYANOFERRATE OF CALCIUM | Anticaking agent | EFSA ADI (group): = 0.03 mg/kg bw/day In a 2-year study, animals frequently showed a higher cell excretion rate in urine samples compared to controls. Since the kidney is known to be the target organ for ferrocyanide toxicity, the Panel considered the increased cell excretion rate indicative for occasional, transient kidney toxicity and identified a NOAEL of 4.4 mg/kg bw per day. Based on this NOAEL of 4.4 mg sodium ferrocyanide/kg bw per day for male rats, the Panel derived an ADI of 0.044 mg sodium ferrocyanide/kg bw per day. Assuming that the toxicity of this compound is due to the ferrocyanide ion only, the Panel established a group ADI for sodium, potassium and calcium ferrocyanide of 0.03 mg/kg bw per day expressed as ferrocyanide ion. The Panel noted that at this ADI the potential amount of free cyanide released would not be of safety concern. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 539 | Sodium thiosulfate Synonyms: SODIUM HYPOSULFITE | Antioxidant, Sequestrant | JECFA (WHO/FAO) 0-0.7 mg/kg bw(1998) Group ADI, expressed as sulfur dioxide, for calcium hydrogen sulfite, calcium metabisulfite, calcium sulfite, potassium hydrogen sulfite, potassium metabisulfite, potassium sulfite, sodium hydrogen sulfite, sodium metabisulfite, sodium sulfite, sodium thiosulfate, and sulfur dioxide JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “SODIUM THIOSULFATE” with food-use authorization under 184.1807 — matched by name, not a shared regulatory number. |
| 541 | Sodium aluminium phosphates | Acidity regulator, Emulsifier, Emulsifying salt, Raising agent, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 542 | Bone phosphate Synonyms: Edible bone phosphate | Anticaking agent, Emulsifier, Humectant, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 550 | Sodium silicates | Anticaking agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 551 | Silicon dioxide, amorphous Synonyms: Silica | Anticaking agent, Carrier, Antifoaming agent | JECFA (WHO/FAO) NOT SPECIFIED(2017) Considered for specification only. An ADI 'not specified' for silicon dioxide and certain silicates was established at the 29th JECFA (1985). JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 552 | Calcium silicate Synonyms: Silicic acid, calcium salt, calcium silicon oxide | Anticaking agent | JECFA (WHO/FAO) NOT SPECIFIED(2015) An ADI 'not specified' for silicon dioxide and certain silicates including calcium silicate was established at the 29th JECFA (1985) JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CALCIUM SILICATE” with food-use authorization under 172.410, 175.300, 176.170, 177.1680 — matched by name, not a shared regulatory number. |
| 553 | Magnesium silicates | Anticaking agent, Glazing agent, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 554 | Sodium aluminosilicate Synonyms: Sodium silicoaluminate, sodium aluminosilicate, aluminium sodium silicate, silicic acid, aluminium sodium salt | Anticaking agent | JECFA (WHO/FAO) NOT SPECIFIED(2017) An ADI 'not specified' for silicon dioxide and certain silicates was established at the 29th JECFA (1985). A PTWI of 2 mg/kg bw for total aluminium was established at the 74th JECFA (2011). The PTWI applies to all aluminium compounds in food, including food additives. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM ALUMINUM SILICATE” with food-use authorization under 182.2727 — matched by name, not a shared regulatory number. |
| 555 | Potassium aluminium silicate Synonyms: Mica,Muscovite | Anticaking agent, Carrier | JECFA (WHO/FAO) NO ADI ALLOCATED(2014) A PTWI of 2 mg/kg bw for total aluminium was established at the 74th JECFA (2011). The PTWI applies to all aluminium compounds in food, including food additives. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 556 | Calcium aluminium silicate Synonyms: ALUMINIUM CALCIUM SILICATE, CALCIUM ALUMINOSILICATE, CALCIUM SILICOALUMINATE, SODIUM CALCIUM SILICOALUMINATE | Anticaking agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 557 | Zinc silicate | Anticaking agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 558 | Bentonite | Anticaking agent | — | Eligible | Eligible Matched “BENTONITE” with food-use authorization under 175.105, 175.300, 176.170, 178.3297 — matched by name, not a shared regulatory number. |
| 559 | Aluminium silicate Synonyms: KAOLIN, LIGHT OR HEAVY | Anticaking agent | EFSA ADI: = 0.14 mg/kg bw/day Reference values, oral absorption and dermal absorption from EFSA conclusion on Aluminium ammonium sulphate (EFSA Journal 2012;10(3):2491). EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 560 | Potassium silicate | Anticaking agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 570 | Fatty acids | Antifoaming agent, Glazing agent, Stabilizer, Foam stabilizer | — | Eligible | Eligible Matched “FATTY ACIDS” with food-use authorization under 172.210, 172.340, 172.822, 172.860 — matched by name, not a shared regulatory number. |
| 574 | Gluconic acid, D- | Acidity regulator, Raising agent | — | Eligible | Not listed Matched “D-GLUCONIC ACID” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 575 | Glucono delta-lactone Synonyms: Gluconolactone, delta-Gluconolactone, GDL, Glucono-delta-lactone | Acidity regulator, Raising agent, Sequestrant | JECFA (WHO/FAO) NOT SPECIFIED(1998) Group ADI for glucono delta-lactone, calcium gluconate, magnesium gluconate, potassium gluconate, and sodium gluconate JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 576 | Sodium gluconate | Sequestrant, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(1998) Group ADI for glucono delta-lactone, calcium gluconate, magnesium gluconate, potassium gluconate, and sodium gluconate JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “SODIUM GLUCONATE” with food-use authorization under 178.1010, 182.6757 — matched by name, not a shared regulatory number. |
| 577 | Potassium gluconate Synonyms: Potassium D-gluconate | Acidity regulator, Sequestrant | JECFA (WHO/FAO) NOT SPECIFIED(1998) Group ADI for glucono delta-lactone, calcium gluconate, magnesium gluconate, potassium gluconate, and sodium gluconate JECFA (WHO/FAO) source ↗ | Eligible | Not listed Matched “POTASSIUM GLUCONATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 578 | Calcium gluconate | Acidity regulator, Firming agent, Sequestrant | JECFA (WHO/FAO) NOT SPECIFIED(1998) Group ADI for glucono delta-lactone, calcium gluconate, magnesium gluconate, potassium gluconate, and sodium gluconate JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CALCIUM GLUCONATE” with food-use authorization under 184.1199 — matched by name, not a shared regulatory number. |
| 579 | Ferrous gluconate | Colour retention agent, Stabilizer | — | Eligible | Eligible Matched “FERROUS GLUCONATE” with food-use authorization under 73.160, 182.80, 184.1308 — matched by name, not a shared regulatory number. |
| 580 | Magnesium gluconate | Acidity regulator, Firming agent, Flavour enhancer | JECFA (WHO/FAO) NOT SPECIFIED(1998) Group ADI for glucono delta-lactone, calcium gluconate, magnesium gluconate, potassium gluconate, and sodium gluconate JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “MAGNESIUM GLUCONATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 585 | Ferrous lactate | Colour retention agent | — | Eligible | Eligible Matched “FERROUS LACTATE” with food-use authorization under 73.165, 184.1311 — matched by name, not a shared regulatory number. |
| 586 | Hexylresorcinol, 4- | Antioxidant, Colour retention agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 620 | Glutamic acid, L(+)- | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 621 | Monosodium L-glutamate Also known as: Ajinomoto Synonyms: SODIUM GLUTAMATE, MSG | Flavour enhancer | JECFA (WHO/FAO) NOT SPECIFIED(1987) Group ADI for L-glutamic acid and its ammonium, calcium, monosodium, magnesium and potassium salts JECFA (WHO/FAO) source ↗EFSA ADI (group): = 30 mg/kg bw/day Based on the NOAEL of 3,200 mg monosodium glutamate/kg bw per day from the neurodevelopmental toxicity study and applying the default uncertainty factor of 100, the Panel derived a group acceptable daily intake (ADI) of 30 mg/kg bw per day, expressed as glutamic acid, for glutamic acid and glutamates (E 620-625). The Panel noted that the exposure to glutamic acid and glutamates (E 620-625) exceeded not only the proposed ADI, but also doses associated with adverse effects in humans for some population groups. EFSA source ↗ | Eligible | Eligible Matched “MONOSODIUM GLUTAMATE” with food-use authorization under 172.320, 182.1 — matched by name, not a shared regulatory number. |
| 622 | Monopotassium L-glutamate Synonyms: POTASSIUM GLUTAMATE, MPG | Flavour enhancer | JECFA (WHO/FAO) NOT SPECIFIED(1987) Group ADI for L-glutamic acid and its monosodium, potassium, calcium, magnesium and ammonium salts JECFA (WHO/FAO) source ↗EFSA ADI (group): = 30 mg/kg bw/day Based on the NOAEL of 3,200 mg monosodium glutamate/kg bw per day from the neurodevelopmental toxicity study and applying the default uncertainty factor of 100, the Panel derived a group acceptable daily intake (ADI) of 30 mg/kg bw per day, expressed as glutamic acid, for glutamic acid and glutamates (E 620-625). The Panel noted that the exposure to glutamic acid and glutamates (E 620-625) exceeded not only the proposed ADI, but also doses associated with adverse effects in humans for some population groups. EFSA source ↗ | Eligible | Eligible Matched “MONOPOTASSIUM GLUTAMATE” with food-use authorization under 172.320, 182.1516 — matched by name, not a shared regulatory number. |
| 623 | Calcium di-L-glutamate Synonyms: CALCIUM GLUTAMATE | Flavour enhancer | JECFA (WHO/FAO) NOT SPECIFIED(1987) Group ADI for L-glutamic acid and its ammonium, calcium, magnesium, monosodium and potassium salts JECFA (WHO/FAO) source ↗EFSA ADI (group): = 30 mg/kg bw/day Based on the NOAEL of 3,200 mg monosodium glutamate/kg bw per day from the neurodevelopmental toxicity study and applying the default uncertainty factor of 100, the Panel derived a group acceptable daily intake (ADI) of 30 mg/kg bw per day, expressed as glutamic acid, for glutamic acid and glutamates (E 620-625). The Panel noted that the exposure to glutamic acid and glutamates (E 620-625) exceeded not only the proposed ADI, but also doses associated with adverse effects in humans for some population groups. EFSA source ↗ | Eligible | Not listed Matched “CALCIUM DIGLUTAMATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 624 | Monoammonium L-glutamate Synonyms: Ammonium glutamate | Flavour enhancer | JECFA (WHO/FAO) NOT SPECIFIED(1987) Group ADI for L-glutamic acid and its ammonium, calcium, sodium, magnesium and potassium salts JECFA (WHO/FAO) source ↗EFSA ADI (group): = 30 mg/kg bw/day Based on the NOAEL of 3,200 mg monosodium glutamate/kg bw per day from the neurodevelopmental toxicity study and applying the default uncertainty factor of 100, the Panel derived a group acceptable daily intake (ADI) of 30 mg/kg bw per day, expressed as glutamic acid, for glutamic acid and glutamates (E 620-625). The Panel noted that the exposure to glutamic acid and glutamates (E 620-625) exceeded not only the proposed ADI, but also doses associated with adverse effects in humans for some population groups. EFSA source ↗ | Eligible | Eligible Matched “MONOAMMONIUM GLUTAMATE” with food-use authorization under 182.1500 — matched by name, not a shared regulatory number. |
| 625 | Magnesium di-L-glutamate Synonyms: MAGNESIUM GLUTAMATE | Flavour enhancer | JECFA (WHO/FAO) NOT SPECIFIED(1987) Group ADI for L-glutamic acid and its monosodium, potassium, calcium, magnesium and ammonium salts; intake limited by laxative action JECFA (WHO/FAO) source ↗EFSA ADI (group): = 30 mg/kg bw/day Based on the NOAEL of 3,200 mg monosodium glutamate/kg bw per day from the neurodevelopmental toxicity study and applying the default uncertainty factor of 100, the Panel derived a group acceptable daily intake (ADI) of 30 mg/kg bw per day, expressed as glutamic acid, for glutamic acid and glutamates (E 620-625). The Panel noted that the exposure to glutamic acid and glutamates (E 620-625) exceeded not only the proposed ADI, but also doses associated with adverse effects in humans for some population groups. EFSA source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 626 | Guanylic acid, 5’- | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 627 | Disodium 5’-guanylate | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 628 | Dipotassium 5’-guanylate | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 629 | Calcium 5’-guanylate | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 630 | Inosinic acid, 5’- | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 631 | Disodium 5’-inosinate | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 632 | Potassium 5’-inosinate | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 633 | Calcium 5’-inosinate | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 634 | Calcium 5’-ribonucleotides | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 635 | Disodium 5’-ribonucleotides | Flavour enhancer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 636 | Maltol Synonyms: 2-METHYLPYROMECONIC ACID, 3-HYDROXY-2-METHYL-4-PYRONE, LARIXINIC ACID | Flavour enhancer | JECFA (WHO/FAO) No safety concern at current levels of intake when used as a flavouring agent(2018) The previously established ADI for maltol was withdrawn by the Committee. JECFA (WHO/FAO) source ↗EFSA ADI: = 1 mg/kg bw/day Considering that JECFA (WHO, 1981, 2006) set an ADI of 1 mg kg/bw per day for this compound, that at least 60% of maltol administered is excreted without being metabolised and that human exposure is around 3 mg/day (5% of the ADI), the FEEDAP Panel considers that the contribution of maltol when used as feed flavouring at the doses considered safe for the target species would not significantly contribute to the ADI. Consequently, no safety concern would arise for the consumer from the use of maltol up to the highest safe level in feeds. EFSA source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “MALTOL” with food-use authorization under 172.515 — matched by name, not a shared regulatory number. |
| 637 | Ethyl maltol Synonyms: 2-Ethyl-3-hydroxy-4-pyrone, 2-Ethyl-3-hydroxy-4h-pyran-4-one, 2-Ethylpyromeconic acid | Flavour enhancer | JECFA (WHO/FAO) 0-2 mg/kg bw (1974)(2005) The ADI established at the eighteenth meeting in 1974 was maintained. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “ETHYL MALTOL” with food-use authorization under 172.515 — matched by name, not a shared regulatory number. |
| 638 | Sodium L-aspartate | Flavour enhancer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 639 | Alanine, DL- | Flavour enhancer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “DL-ALANINE” with food-use authorization under 172.540 — matched by name, not a shared regulatory number. |
| 640 | Glycine Synonyms: AMINOACETIC ACID, GLYCOLL, AMINOETHANOIC ACID | Flavour enhancer | — | Eligible | Eligible Matched “GLYCINE” with food-use authorization under 172.320, 172.812 — matched by name, not a shared regulatory number. |
| 641 | Leucine, L- | Flavour enhancer | — | Eligible | Eligible Matched “L-LEUCINE” with food-use authorization under 172.320, 172.804 — matched by name, not a shared regulatory number. |
| 642 | Lysin hydrochloride | Flavour enhancer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 650 | Zinc acetate | Flavour enhancer | — | Eligible | Not listed Matched “ZINC ACETATE” in the FDA inventory, but only under drug/cosmetic/device-use citations (175.105), not as a direct food additive — matched by name, not a shared regulatory number. |
| 900a | Polydimethylsiloxane Synonyms: Poly(dimethylsiloxane), dimethylpolysiloxane, dimethylsilicone fluid,
dimethylsilicone oil, dimethicone | Anticaking agent, Antifoaming agent, Emulsifier | JECFA (WHO/FAO) 0–1.5 mg/kg bw(2011) The Committee withdrew the temporary ADI of 0–0.8 mg/kg body weight per day and re-established the ADI of 0–1.5 mg/kg body weight, originally established at the eighteenth meeting. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “DIMETHYLPOLYSILOXANE” with food-use authorization under 173.340, 175.105, 175.300, 176.170 — matched by name, not a shared regulatory number. |
| 900b | Methylphenylpolysiloxane | Antifoaming agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 901 | Beeswax | Carrier, Emulsifier, Glazing agent, Stabilizer, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2005) No safety concern at the predicted dietary exposure (less than 650 mg/person per day), based on the long history of use and lack of toxicity observed with the major components of beeswax. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “BEESWAX” with food-use authorization under 184.1973 — matched by name, not a shared regulatory number. |
| 902 | Candelilla wax | Carrier, Emulsifier, Glazing agent, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2005) No safety concern at the predicted dietary exposure (less than 650 mg/person per day). JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “CANDELILLA WAX (WAX FROM STEMS AND BRANCHES OF EUPHORBIA CERIFERA)” with food-use authorization under 175.105, 175.320, 176.180, 184.1976 — matched by name, not a shared regulatory number. |
| 903 | Carnauba wax | Acidity regulator, Anticaking agent, Bulking agent, Carrier, Glazing agent | Eligible | Eligible Matched “CARNAUBA WAX (COPERNICIA CERIFERA (ARRUDA) MART.)” with food-use authorization under 175.320, 184.1978 — matched by name, not a shared regulatory number. | |
| 904 | Shellac, bleached | Glazing agent | JECFA (WHO/FAO) NOT SPECIFIED(1992) Present uses (as a coating, glazing, and surface-finishing agent externally applied to food) not of toxicological concern JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 905a | Mineral oil, food grade | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 905b | Petroleum jelly (Petrolatum) | Antifoaming agent, Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 905c | Petroleum wax | Glazing agent, Antifoaming agent | — | Eligible | Eligible Matched “PETROLEUM WAX” with food-use authorization under 172.230, 172.615, 172.842, 172.886 — matched by name, not a shared regulatory number. |
| 905d | Mineral oil, high viscosity | Antifoaming agent, Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 905e | Mineral oil, medium viscosity | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 905f | Mineral oil, medium and low viscosity, class II | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 905g | Mineral oil, medium and low viscosity, class III | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 906 | Benzoin gum Synonyms: BENZOIN RESIN | Glazing agent | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 907 | Hydrogenated poly-1-decenes | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 908 | Rice bran wax | Glazing agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “RICE BRAN WAX” with food-use authorization under 172.615, 172.890, 178.3860 — matched by name, not a shared regulatory number. |
| 909 | Spermaceti wax | Glazing agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 910 | Wax esters | Glazing agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 911 | Methyl esters of fatty acids | Glazing agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 913 | Lanolin | Glazing agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “LANOLIN” with food-use authorization under 172.615, 175.300, 176.170, 176.180 — matched by name, not a shared regulatory number. |
| 915 | Glycerol, methyl, or pentaerithrytol esters of colophane | Glazing agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 916 | Calcium iodate | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CALCIUM IODATE” with food-use authorization under 184.1206 — matched by name, not a shared regulatory number. |
| 917 | Potassium iodate | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “POTASSIUM IODATE” with food-use authorization under 184.1635 — matched by name, not a shared regulatory number. |
| 918 | Nitrogen oxides | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “NITROGEN OXIDES” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 919 | Nitrosyl chloride | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “NITROSYL CHLORIDE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 920 | Cysteine, L- and its hydrochlorides – sodium and potassium salts | Flour treatment agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 921 | Cystine, L-and its hydrochlorides sodium and potassium salts | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 922 | Potassium persulfate | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “POTASSIUM PERSULFATE” with food-use authorization under 172.210, 175.105, 175.210, 176.170 — matched by name, not a shared regulatory number. |
| 923 | Ammonium persulfate | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “AMMONIUM PERSULFATE” with food-use authorization under 172.892, 175.105, 176.170, 177.1200 — matched by name, not a shared regulatory number. |
| 925 | Chlorine | Flour treatment agent, Bleaching agent | EFSA TDI: = 0.15 mg/kg bw/day The WHO guidelines for drinking-water quality set a guideline value of 5 mg/L for chlorine based on a TDI of 0.150 mg/kg bw, allocating 100% of this TDI to water and assuming a 60 kg bw individual consumes 2 litres of water per day (WHO, 2004). EFSA source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “CHLORINE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 926 | Chlorine dioxide Synonyms: CHLORINE (IV) OXIDE, CHLORINE PEROXIDE | Flour treatment agent | EFSA TDI: = 0.03 mg/kg bw/day The International Programme on Chemical Safety (IPCS) derived a tolerable daily intake (TDI) value expressed as chlorine of 0.03 mg/kg bw. EFSA source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CHLORINE DIOXIDE” with food-use authorization under 173.300, 178.1010 — matched by name, not a shared regulatory number. |
| 927a | Azodicarbonamide Synonyms: Azobisformamide | Flour treatment agent | JECFA (WHO/FAO) ADI NO LONGER SUPPORTED AS THERE IS NO SUPPORT FOR A RE-EVALUATION(2023) As safety concern has been raised on the safe use of azodicarbonamide and no support was found to provide data for a re-evaluation CCFA53 withdrew the ADI. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “AZODICARBONAMIDE” with food-use authorization under 172.806, 177.1210, 177.2600, 178.3010 — matched by name, not a shared regulatory number. |
| 927b | Urea (Carbamide) | Flour treatment agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 928 | Benzoyl peroxide Synonyms: Benzoyl superoxide | Bleaching agent, Flour treatment agent, Preservative | JECFA (WHO/FAO) NOT SPECIFIED(2004) Treatment of whey with benzoyl peroxide at a maximum concentration of 100 mg/kg does not pose a safety concern. JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “BENZOYL PEROXIDE” with food-use authorization under 172.814, 175.105, 176.170, 177.2420 — matched by name, not a shared regulatory number. |
| 929 | Acetone peroxide | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “ACETONE PEROXIDES” with food-use authorization under 172.802 — matched by name, not a shared regulatory number. |
| 930 | Calcium peroxide Synonyms: Calcium dioxide (misnomer) | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “CALCIUM PEROXIDE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 940 | Dichlorodifluormethane | Propellant, Foaming agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 941 | Nitrogen | Packaging gas, Propellant | Eligible | Eligible Matched “NITROGEN” with food-use authorization under 177.1615, 184.1540 — matched by name, not a shared regulatory number. | |
| 942 | Nitrous oxide Synonyms: NITROGEN OXIDE, DINITROGEN MONOXIDE | Antioxidant, Foaming agent, Packaging gas, Propellant | JECFA (WHO/FAO) NOT SPECIFIED(2000) At its twenty-ninth meeting (1985), the Committee concluded that use of nitrous oxide as a propellant for food was acceptable. At its fifty-fifth meeting (2000), the Committee was requested by the Codex Committee on Food Additives and Contaminants to evaluate the additional use of nitrous oxide as a packaging gas, but the Committee could not carry out this request because no information on intake of nitrous oxide for such use was available. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “NITROUS OXIDE” with food-use authorization under 184.1545 — matched by name, not a shared regulatory number. |
| 943a | Butane | Propellant | — | Eligible | Eligible Matched “N-BUTANE” with food-use authorization under 173.350, 184.1165 — matched by name, not a shared regulatory number. |
| 943b | Isobutane | Propellant | — | Eligible | Eligible Matched “ISOBUTANE” with food-use authorization under 184.1165 — matched by name, not a shared regulatory number. |
| 944 | Propane | Propellant | — | Eligible | Eligible Matched “PROPANE” with food-use authorization under 173.350, 184.1655 — matched by name, not a shared regulatory number. |
| 945 | Chloropentafluorethane | Propellant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 946 | Octafluorcyclobutane | Propellant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 949 | Hydrogen | Packaging gas | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 950 | Acesulfame potassium Synonyms: ACESULFAME K | Flavour enhancer, Sweetener | EFSA ADI: = 9 mg/kg bw/day The EU Scientific Committee on Food (SCF) established an ADI of 9 mg/kg bw for acesulfame K in 1984 (SCF, 1985) based on a chronic study in the dog. In 2000, SCF reaffirmed the ADI of 0-9 mg/kg bw per day for acesulfame K confirming the appropriateness of the dog species (SCF, 2000). EFSA source ↗ | Eligible | Eligible Matched “ACESULFAME POTASSIUM” with food-use authorization under 172.800 — matched by name, not a shared regulatory number. |
| 951 | Aspartame Synonyms: Aspartyl phenylalanine methyl ester | Flavour enhancer, Sweetener | JECFA (WHO/FAO) 0–40 mg/kg bw(2023) Overall, JECFA concluded that there was no convincing evidence from experimental animal or human data that aspartame has adverse effects after ingestion. This conclusion is underpinned by the information that aspartame is fully hydrolysed in the gastrointestinal tract into metabolites that are identical to those absorbed after consumption of common foods, and that no aspartame enters the systemic circulation. JECFA concluded that the data evaluated at the present meeting indicated no reason to change the previously established ADI of 0–40 mg/kg bw for aspartame. JECFA therefore reaffirmed the ADI of 0–40 mg/kg bw for aspartame at the present meeting. JECFA (WHO/FAO) source ↗EFSA ADI: = 40 mg/kg bw/day The Panel concluded that aspartame was not of safety concern at the current aspartame exposure estimates or at the ADI of 40 mg/kg bw/day. Therefore, there was no reason to revise the ADI of aspartame. Current exposures to aspartame - and its degradation product 5-benzyl-3,6-dioxo-2-piperazine acetic acid (DKP) - were below their respective ADIs. The ADI is not applicable to Phenylketonuria (PKU) patients. These individuals require total control of dietary phenylalanine intake to manage the risk from elevated phenylalanine plasma levels. EFSA source ↗ | Eligible | Eligible Matched “ASPARTAME” with food-use authorization under 172.804 — matched by name, not a shared regulatory number. |
| 952 | Cyclamates Also known as: Cyclamate | Sweetener | — | Eligible | Excluded Matched “CYCLAMATE--PROHIBITED” in 21 CFR Part 189 (Substances Prohibited From Use in Human Food) — matched by name, not a shared regulatory number. |
| 953 | Isomalt (Hydrogenated isomaltulose) | Anticaking agent, Bulking agent, Glazing agent, Stabilizer, Sweetener, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 954 | Saccharins | Sweetener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 955 | Sucralose (Trichlorogalactosucrose) | Sweetener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 956 | Alitame | Sweetener | JECFA (WHO/FAO) 0-1 mg/kg bw (1996)(2002) The ADI of 0-1 mg/kg bw that was established at the forty-sixth meeting (1996) was maintained at the fifty-ninth meeting (2002). JECFA (WHO/FAO) source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 957 | Thaumatin | Flavour enhancer, Sweetener | JECFA (WHO/FAO) NOT SPECIFIED (group ADI including thaumatin and thaumatin II)(2025) Based on the amino acid sequence similarity of thaumatin I, thaumatin II and recombinant thaumatin II, JECFA revised the ADI “not specified” for thaumatin (INS No. 957) to a group ADI “not specified” including thaumatin (INS No. 957) and thaumatin II produced by recombinant methods in the seeds of the tobacco plant Nicotiana tabacum. JECFA (WHO/FAO) source ↗ | Eligible | Not listed Matched “THAUMATIN” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 958 | Glycyrrhizin | Flavour enhancer, Sweetener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 959 | Neohesperidine dihydrochalcone | Sweetener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 960 | Steviol glycosides | Sweetener | JECFA (WHO/FAO) 0–4 mg/kg bw(2026) No new information was identified in the literature that would indicate a need to revise the current ADI for steviol glycosides. The current ADI of 0–4 mg/kg bw, expressed as steviol, was confirmed. JECFA concluded that the evaluated enzymes and protein present in the production strains are unlikely to be toxins and have not been detected in the purified rebaudioside M preparations produced by two separate methods. JECFA (WHO/FAO) source ↗EFSA ADI: = 4 mg/kg bw/day Both the JECFA and EFSA established an ADI for steviol glycosides (including rebaudioside A), expressed as steviol equivalents, of 4 mg/kg bw/day. EFSA source ↗ | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 961 | Neotame | Flavour enhancer, Sweetener | JECFA (WHO/FAO) 0-2 mg/kg bw(2003) JECFA established an ADI of 0–2 mg/kg of body weight for neotame on the basis of a NOEL of 200 mg/kg of body weight per day in a 1-year study in dogs and a 100-fold safety factor. JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “NEOTAME” with food-use authorization under 172.829 — matched by name, not a shared regulatory number. |
| 962 | Aspartame-acesulfame salt Synonyms: Aspartame-acesulfame salt | Sweetener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 963 | Tagatose, D- | Sweetener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 964 | Polyglycitol syrup Synonyms: Hydrogenated starch hydrolysate, Polyglucitol | Sweetener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 965 | Maltitols | Bulking agent, Emulsifier, Humectant, Sweetener, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 966 | Lactitol Synonyms: Lactit, Lactositol, Lactobiosit | Emulsifier, Sweetener, Thickener | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 967 | Xylitol | Emulsifier, Humectant, Stabilizer, Sweetener, Thickener | Eligible | Eligible Matched “XYLITOL” with food-use authorization under 172.395 — matched by name, not a shared regulatory number. | |
| 968 | Erythritol Synonyms: meso-Erythritol, Tetrahydroxybutane, Erythrite | Flavour enhancer, Humectant, Sweetener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 969 | Advantame | Sweetener, Flavour enhancer | EFSA ADI: = 5 mg/kg bw/day Conservative estimates of advantame exposure for high level adults and children consumers were below the ADI for the proposed use levels. EFSA source ↗ | Eligible | Eligible Matched “ADVANTAME” with food-use authorization under 172.803 — matched by name, not a shared regulatory number. |
| 999 | Quillaia extracts Synonyms: SOAPBARK EXTRACT, QUILLAY BARK EXTRACT, PANAMA BARK EXTRACT, QUILLAI EXTRACT, BOIS DE PANAMA | Emulsifier, Foaming agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1000 | Cholic acid | Emulsifier | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “CHOLIC ACID” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. | |
| 1001 | Choline salts and esters | Emulsifier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1100 | Amylases | Flour treatment agent | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1101 | Proteases | Flour treatment agent, Flavour enhancer, Stabilizer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1102 | Glucose oxidase | Antioxidant | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1103 | Invertases | Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1104 | Lipases | Flavour enhancer | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1105 | Lysozyme | Preservative | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1200 | Polydextroses Synonyms: MODIFIED POLYDEXTROSES | Bulking agent, Glazing agent, Humectant, Stabilizer, Thickener | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). | |
| 1201 | Polyvinylpyrrolidone Synonyms: Povidone, PVP | Emulsifier, Glazing agent, Stabilizer, Thickener | Eligible | Eligible Matched “POLYVINYLPYRROLIDONE” with food-use authorization under 73.1, 73.1001, 172.210, 173.55 — matched by name, not a shared regulatory number. | |
| 1202 | Polyvinylpyrrolidone, insoluble | Colour retention agent, Stabilizer | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1203 | Polyvinyl alcohol Synonyms: VINYL ALCOHOL POLYMER, PVOH | Glazing agent, Thickener | Eligible | Eligible Matched “POLYVINYL ALCOHOL” with food-use authorization under 73.1, 175.105, 175.300, 175.320 — matched by name, not a shared regulatory number. | |
| 1204 | Pullulan | Glazing agent, Thickener | JECFA (WHO/FAO) NOT SPECIFIED(2011) Dietary exposure to pullulan as a dietary fibre could reach 1g/kg body weight per day for children (2–5 years old) and 0.4 g/kg body weight per day for the general population (2 years of age and older). These estimates are 8 and 20 times lower, respectively, than the no-observed-effect level (NOEL) observed in the 90-day rat study evaluated previously. Gastrointestinal effects observed in humans should be taken into account when considering appropriate use levels. The Committee stressed that it assessed the safety of use and not the efficacy of pullulan used as a dietary fibre. The Committee maintained the previously established ADI “not specified”c for the previously evaluated food additive uses. JECFA (WHO/FAO) source ↗ | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1205 | Methacrylate copolymer, basic | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1206 | Methacrylate copolymer, neutral | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1207 | Methacrylate copolymer, anionic | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1208 | Polyvinylpyrrolidone-vinyl acetate copolymer | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1209 | Polyvinyl alcohol (PVA)-polyethylene glycol (PEG) graft co-polymer | Glazing agent | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1400 | Dextrins, roasted starch | Carrier, Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1401 | Acid-treated starch | Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “STARCH, ACID MODIFIED” with food-use authorization under 172.892, 182.90 — matched by name, not a shared regulatory number. |
| 1402 | Alkaline treated starch Synonyms: Starch, Alkaline treated | Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1403 | Bleached starch Synonyms: Starch, bleached | Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “STARCH, BLEACHED” with food-use authorization under 172.892 — matched by name, not a shared regulatory number. |
| 1404 | Oxidized starch Synonyms: STARCH, OXIDIZED | Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: OXIDIZED STARCHES” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1405 | Starches, | Enzyme, Emulsifier, Stabilizer, Thickener | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1410 | Monostarch phosphate | Emulsifier, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1411 | Distarch glycerol | Emulsifier, Stabilizer, Thickener | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed Matched “STARCH, FOOD, MODIFIED: DISTARCH GLYCEROL” in the FDA inventory, but only under drug/cosmetic/device-use citations (175.105), not as a direct food additive — matched by name, not a shared regulatory number. | |
| 1412 | Distarch phosphate | Emulsifier, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1413 | Phosphated distarch phosphate | Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: PHOSPHATED DISTARCH PHOSPHATE” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1414 | Acetylated distarch phosphate | Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: ACETYLATED DISTARCH PHOSPHATE” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1420 | Starch acetate | Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: STARCH ACETATE” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1422 | Acetylated distarch adipate | Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: ACETYLATED DISTARCH ADIPATE” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1440 | Hydroxypropyl starch | Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: HYDROXYPROPYL STARCH” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1442 | Hydroxypropyl distarch phosphate | Anticaking agent, Emulsifier, Stabilizer, Thickener | — | Eligible | Eligible Matched “STARCH, FOOD, MODIFIED: HYDROXYPROPYL DISTARCH PHOSPHATE” with food-use authorization under 172.892, 175.105 — matched by name, not a shared regulatory number. |
| 1450 | Starch sodium octenyl succinate | Emulsifier, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1451 | Acetylated oxidized starch | Emulsifier, Stabilizer, Thickener | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1452 | Starch aluminium octenyl succinate | Anticaking agent, Carrier, Stabilizer, Flavour enhancer, Sweetener, Acidity regulator, Preservative, Emulsifier, Sequestrant, Flour treatment agent, Bulking agent, Glazing agent, Gelling agent, Humectant, Thickener, Foaming agent, Colour, Colour retention agent, Firming agent, Raising agent, Emulsifying salt, Antioxidant, Bleaching agent, Propellant, Antifoaming agent, Carbonating agent, Packaging gas, Foam stabilizer, Antimicrobial preservative, Modified starch, Enzyme | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1503 | Castor oil Synonyms: Ricinus oil | Anticaking agent, Carrier, Emulsifier, Glazing agent | Not listed Not listed in the EU's Annex II Part B positive list. | Eligible Matched “CASTOR OIL (RICINUS COMMUNIS L.)” with food-use authorization under 73.1, 172.510, 172.876, 175.105 — matched by name, not a shared regulatory number. | |
| 1504 | Cyclotetraglucose | Carrier | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1505 | Triethyl citrate Synonyms: Ethyl citrate, Triethyl 2-hydroxy-1,2,3-propane tricarboxylate | Carrier, Emulsifier, Stabilizer, Foam stabilizer, Sequestrant | JECFA (WHO/FAO) Not evaluated(2023) JECFA requests that updated exposure data (including both MSDI and SPET values) be provided for the flavouring agents citronelloxyacetaldehyde (No. 592), 1,3-nonanediol acetate (No. 605), levulinic acid (No. 606), hydroxycitronellal diethyl acetal (No. 613), diethyl malonate (No. 614), diethyl tartrate (No. 622) and triethyl citrate (No. 629) within 2 years (i.e. by December 2025) so that a re-evaluation of these previously evaluated compounds can be completed. JECFA (WHO/FAO) source ↗ | Eligible | Not listed Matched “TRIETHYL CITRATE” in the FDA inventory, but with no citation clearly establishing direct food-additive status — matched by name, not a shared regulatory number. |
| 1517 | Glycerol diacetate Synonyms: DIACETIN | Carrier | — | Eligible | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |
| 1518 | Triacetin Synonyms: Glyceryl triacetate, Triacetyl glycerine, Enzactin | Carrier, Emulsifier, Humectant | JECFA (WHO/FAO) NOT SPECIFIED (1975)(2002) No safety concern at current levels of intake when used as a flavouring agent JECFA (WHO/FAO) source ↗ | Eligible | Eligible Matched “TRIACETIN (GLYCEROL TRIACETATE)” with food-use authorization under 175.300, 175.320, 181.27, 184.1901 — matched by name, not a shared regulatory number. |
| 1519 | Benzyl alcohol Synonyms: Phenyl carbinol, Phenylmethyl alcohol, alpha-Hydroxytoluene, Benzenemethanol | Carrier | EFSA ADI: = 4 mg/kg bw/day Based on the toxicological database available, the Panel established the ADI of 4 mg/kg bw per day for benzyl alcohol (E 1519) and concluded that the exposure to benzyl alcohol (E 1519) does not raise a safety concern at the reported uses and use levels. EFSA source ↗ | Eligible | Eligible Matched “BENZYL ALCOHOL” with food-use authorization under 73.1001, 172.515, 175.105, 175.300 — matched by name, not a shared regulatory number. |
| 1520 | Propylene glycol Synonyms: 1,2-DIHYDROXYPROPANE, METHYL GLYCOL, PROPANEDIOL | Emulsifier, Glazing agent, Humectant | JECFA (WHO/FAO) 0-25 mg/kg bw (1973)(2002) Evaluation not finalized, pending definition of "flavouring agent" JECFA (WHO/FAO) source ↗EFSA ADI: = 25 mg/kg bw/day The Panel considered that for the food categories for which information was available, the exposure was likely to be overestimated. Considering the toxicity database, the Panel concluded that there was no reason to revise the current ADI of 25 mg/kg bw per day (SCF). The Panel also concluded that the mean and the high exposure levels (P95) of the brand-loyal refined exposure scenario did not exceed the ADI in any of the population groups from the use of propane-1,2-diol (E 1520) at the reported use levels and analytical results. EFSA source ↗ | Eligible | Eligible Matched “PROPYLENE GLYCOL” with food-use authorization under 73.30, 175.300, 175.320, 176.180 — matched by name, not a shared regulatory number. |
| 1521 | Polyethylene glycol | Antifoaming agent, Carrier, Emulsifier, Glazing agent, Thickener | — | Eligible | Eligible Matched “POLYETHYLENE GLYCOL (M W 200-9,500)” with food-use authorization under 73.1, 172.210, 172.820, 173.310 — matched by name, not a shared regulatory number. |
| 1522 | Calcium lignosulfonate, 40-65 | Carrier, Modified starch | — | Not listed Not listed in the EU's Annex II Part B positive list. | Not listed No name match found in the FDA's Substances Added to Food inventory (a partial list by FDA's own description — absence doesn't necessarily mean prohibited, only that this database has no specific record; matched by name, not a shared regulatory number). |